Your liver is just under three years old

The liver has a unique ability to regenerate after damage. However, it was unknown whether this ability decreases as we age. Scientists have now used a technique known as retrospective radiocarbon birth dating to determine the age of the human liver. They showed that no matter the person's age, the liver is always on average less than three years old. The results demonstrate that aging does not influence liver renewal, making the liver an organ that generally replaces its cells equally well in young and old people.

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The secret to a longer lifespan? Gene regulation holds a clue

Researchers investigated genes connected to lifespan. Their research uncovered specific characteristics of these genes and revealed that two regulatory systems controlling gene expression -- circadian and pluripotency networks -- are critical to longevity. The findings have implications both in understanding how longevity evolves and in providing new targets to combat aging and age-related diseases.

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Dementia diagnosis often comes as part of costly crisis

Medicare costs around the time of a dementia diagnosis are much lower for older adults screened proactively rather than those diagnosed while experiencing a health issue.

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Researchers investigate the links between facial recognition and Alzheimer's disease

In recent years Alzheimer's disease has been on the rise throughout the world and is rarely diagnosed at an early stage when it can still be effectively controlled. Using artificial intelligence, researchers conducted a study to identify whether human-computer interfaces could be adapted for people with memory impairments to recognize a visible object in front of them.

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Too much self-confidence can endanger health

Older people who overestimate their health go to the doctor less often. This can have serious consequences for their health, for example, when illnesses are detected too late. By contrast, people who think they are sicker than they actually are visit the doctor more often. This is what a new study based on data from over 80,000 Europeans aged 50 and older found.

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Painter is Brightening City’s Drab and Neglected Streets Transforming Them into a Rainbow

A talented artist has been brightening up her city’s streets for four years—turning rundown and neglected buildings into a rainbow of colors. Tash Frootko has transformed 25 houses in Gloucester so far, painting her way into residents’ hearts. The huge project, finally unveiled this week, marks a milestone in her mission to inject color into […]

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Sisters Find Each Other After 45 Years Apart – Living in the Same City With Sons Going to the Same School

They share the same father, are the same age, and have lived in the same city for over 30 years. Yet, each sister was unaware of the other’s existence, having been born to different mothers separated through unfortunate circumstances 51 years ago. They’ve reunited recently, however, after a DNA test, and it’s absolutely spooky how […]

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Seven healthy habits linked to lower risk of dementia in those with genetic risk

Seven healthy habits and lifestyle factors may play a role in lowering the risk of dementia in people with the highest genetic risk, according to new research.

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Missing link between Alzheimer's and vascular disease found?

A gene called FMNL2 may explain why people with hypertension, diabetes, heart disease, or obesity have a greater risk of developing Alzheimer's disease.

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Scientists identify how the brain links memories

Our brains lose the ability to link related memories as we age. Scientists genetically restored this brain function in middle-aged mice and identified an FDA-approved drug that achieves the same thing.  The study suggests a new approach for combating middle-aged memory loss and a possible early intervention for dementia.

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GNN Brings Good News Headlines to 120 Schools in Partnership With Digital Signage Company

With childhood depression and anxiety rising during the pandemic and disturbing news stories only adding to the mental health burden in our schools, it is the perfect time to be delivering some positive news headlines into hallways and classrooms across the U.S. That’s exactly what Good News Network is now providing in a new partnership […]

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Drug that lowers blood sugar also reduces blood vessel dysfunction caused by aging

An FDA-approved drug to lower blood sugar in adults with Type 2 diabetes also may decrease blood vessel dysfunction associated with aging, according to a new study.

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All-Black Climbing Team Makes History Reaching Top of Everest, Inspiring Diverse Adventurers

This month, seven members of an all-Black mountain climbing team summited Mount Everest, helped along by eight Sherpa guides. Even though hundreds line up to climb Everest every year, only ten Black people have surmounted the highest peak on Earth before, including only one Black woman, and one Black American. “I am deeply honored to […]

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Type 2 diabetes accelerates brain aging and cognitive decline

Scientists have demonstrated that normal brain aging is accelerated by approximately 26% in people with progressive type 2 diabetes compared with individuals without the disease, reports a new study.

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Living with dogs (but not cats) as a toddler might protect against Crohn's disease

Young children who grow up with a dog or in a large family may have some protection later in life from a common inflammatory bowel disease known as Crohn's disease, according to a new study.

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Londoner Recruits Real Italian Moms and Grandmas to Be Rotating Cooks at His Restaurant, ‘La Mia Mamma’

A homesick London restauranteur decided to the ditch the employment of culinary school graduates, and start hiring that almost mythical allegory of culinary folklore—the Italian grandmother. For Peppe Corsaro, this return to his roots was met with huge success in the London restaurant scene, and has brought dozens of mammas from all regions of Italy. […]

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Parents Are Most Proud of Their Child’s Ability to Show Empathy and Kindness, Says New Poll

Parents are most proud of their child’s ability to be compassionate, display kindness, and go above and beyond to help and support a friend. A poll of 1,000 parents, with kids aged three to seven, also revealed seeing their offspring demonstrate selfless qualities evoked feelings of pride. On average, children left their moms and dads […]

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Ashes Scattered After Her Dog Dies Form “Miraculous” Shape in the Wind: ‘They Never Truly Leave Us’

A photo shared on Reddit went viral when thousands of people got emotional at the sight, and others were flooded with memories of pets gone by. The picture (and video below) shows a woman scattering the ashes of her beloved dog, Biscuit, at a local park. She called it a “miracle” after seeing the handful […]

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Deaf-Blind Communities Have Created a New Language of Touch

Growing for years out of a special group of humans in Washington state, a new human language—pro-tactile ASL, has gained recognition. Born from the spirit of human connection, those who can neither see nor hear use another person’s body as the canvass on which to communicate a nearly infinite-number of ideas, feelings, or just an […]

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Scientist uncovers clues to aging in mitochondria

Many age-related diseases share a common feature: the mitochondria of cells begin to malfunction. While the cause is not known, scientists have discovered a new mechanism of how mitochondria start to go wrong, which opens new doors for researchers to explore how to begin to fix the problem.

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Diving Heroes Find Woman’s 100-Year-old Wedding Ring After it Flew Off her Finger Into a River

A team of scuba diving heroes have reunited a grateful woman with her lost antique wedding ring after it flew off her finger—and into a river. Emma Lyon was watching a regatta from the banks of the River Great Ouse last Saturday when the 100-year-old jewelery flew into the water. The gold wedding ring had […]

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Stimulating brain circuits promotes neuron growth in adulthood, improving cognition and mood

Targeting specific brain cells modulated memory retrieval and altered anxiety-like behaviors in mice. Essentially, scientists boosted the electrical activity between cells in the hypothalamus and the hippocampus to create new neurons -- an important process called neurogenesis.

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One Man’s Treasure Hunt Thrilled a Canadian Town, Turning Strangers into Friends

A horror-themed treasure hunt, organized anonymously in a small Canadian town, left the community enriched with funds and friends. The town in question, Miramichi in New Brunswick, has a history replete with scary stories of murder and ghosts, which the hunt’s organizer used as context to keep the spooky search going all the way up […]

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Robotic surgery is safer and improves patient recovery time

Robot-assisted surgery used to perform bladder cancer removal and reconstruction enables patients to recover far more quickly and spend significantly (20 per cent) less time in hospital, concludes a new clinical trial.

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Baby Blanket Crocheted by Queen Mary and Surviving WWII Set to Raise Money for Ukraine Children’s Fund

A baby blanket which was crocheted by Queen Mary and survived World War II is being sold to raise money to help children in Ukraine. Great-grandmother Kathleen Pritchard was wrapped in the pink shawl as a baby after her mother Florence won a contest. Two blankets, one pink and one blue, were knitted by Queen […]

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Power of Internet Reunites Minneapolis Woman With Refugee She’d Given $100 to, Decades Ago

23-years ago, a cash gift of $100 from a generous American aboard an airline flight inspired hope in a pair of young women fleeing the former-Yugoslavia during the country’s collapse. After two decades, they wanted to find the mysterious woman again, but they only knew her first name—Tracy. Now, after some amateur sleuthing and their […]

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New measure of sperm age may be predictor of pregnancy success

A novel technique to measure the age of male sperm has the potential to predict the success and time it takes to become pregnant, according to a newly published study.

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A single hormone directs body's responses to low-protein diet

A single hormone appears to coordinate the lifespan extension produced by a low-protein diet. Low-protein diets produce beneficial metabolic effects in aged mice, improving metabolic health, reducing frailty, and extending lifespan. These beneficial effects were also apparent when protein intake was reduced in middle-aged mice, even protecting against the detriments of obesity. Importantly, these beneficial effects were lost in mice that lacked FGF21, suggesting that its action in the brain is critical for the increase in health and lifespan.

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Taking ownership of your health

Researchers show that making healthy lifestyle choices relating to diet, exercise, alcohol intake, smoking status, sleep duration, and weight management result in a longer lifespan. The benefits of healthy choices were also seen among older individuals and those with one or more serious chronic health conditions. These findings will help inform the development of healthcare practices and policies that educate patients about the benefits of making healthy lifestyle choices.

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Family size may influence cognitive functioning in later life

A new study found that having three or more versus two children has a negative effect on late-life cognition. The results further indicated that this effect was strongest in Northern Europe, where higher fertility decreases financial resources but does not improve social resources in this region.

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A Passenger With No Flying Experience Landed a Plane Like a Pro

Whether you’ve seen it on Airplane! or tested on Mythbusters, it is possible for a passenger with no flying experience to land an airplane if there’s a calm voice on the radio telling them how. That’s what happened recently aboard a small single-engine plane, when the incapacitation of the pilot left a passenger at the wheel. Radioing down to […]

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Dementia: Combination of 'feelings' and measurements suggest Alzheimer's in the early stage

Subjective memory disorders in conjunction with conspicuous levels of beta-amyloid proteins in the cerebrospinal fluid are a strong indication of developing Alzheimer's disease. This is the conclusion of a new study involving about 1,000 older adults.

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How a leaky gut leads to inflamed lungs

In addition to increased morbidity and impaired lung function after a Streptococcus pneumoniaeinfection in older mice, the researchers also found elevated levels of gut-derived bacteria in the lungs, suggesting that bacteria that migrate from the intestine to the lungs may partially be responsible for the poor outcomes in older individuals.

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Tiny Bomb-Sniffing Jack Russell is a National Hero, Sporting a Presidential Medal

Helping to sweep 200 explosive devices in Ukraine, Patron the Jack Russel recently received a presidential medal from President Zelenskyy. Meaning “Ammo” in Ukrainian, Patron’s handler, Mykhailo Iliev of the Civil Protection Service, accepted the medal on the two-year-old pooch’s behalf in a news conference that included Canadian prime minister Justin Trudeau. “Today, I want […]

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Methylation of tRNA-derived fragments regulates gene-silencing activity in bladder cancer

Researchers describe a novel form of gene regulation that is altered in bladder cancer, leading to the boosting of a gene pathway that helps the cancer cells survive during rapid growth. The work focuses on a 22-base fragment of transfer RNA, tRF-3b, which is modified by the enzyme complex TRMT6/61A. In bladder cancer, the levels of TRMT6/61A -- a methyltransferase -- are elevated. The methylation modification prevents tRF-3bs from silencing the expression of various genes in the unfolded protein response pathway in the cancer cells.

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Quantifying cognitive decline in dogs could help humans with Alzheimer's disease

Researchers have found that a suite of complimentary tests can quantify changes in dogs suspected of suffering from cognitive decline. The approach could not only aid owners in managing their elderly canine's care, but could also serve as a model for evaluating cognitive decline progression in -- and treatments for -- humans with Alzheimer's disease.

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Watch the Moment of Rescue for a Little Dog Trapped Down Hole And Missing For Days

Flossie the pooch suddenly vanished from her home in Devon, England—and several days went by before anyone heard anything. On Monday, Bracken Jelier posted a plea on Facebook, telling friends and family to keep an eye out. Finally, on Thursday afternoon, Flossie was located—but she was stuck down a rabbit hole in a neighbor’s garden […]

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Irish Woman Who Won $145M Lottery Has Given Over Half: ‘I’m Addicted to Helping People’

A self-confessed charity addict won more than $145 million (£115) million in the lottery, allowing her to overdose on her admitted addiction. Making news headlines around the UK and Ireland, Frances Connelly has already given away ($74 million) £60 million with her husband, “Patty” Patrick, who actually bought the winning lottery ticket. “Helping people… it […]

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'Stressed' cells offer clues to eliminating build-up of toxic proteins in dementia

It's often said that a little stress can be good for you. Now scientists have shown that the same may be true for cells, uncovering a newly-discovered mechanism that might help prevent the build-up of tangles of proteins commonly seen in dementia. Scientists have identified a new mechanism that appears to reverse the build-up of aggregates, not by eliminating them completely, but rather by 'refolding' them.

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Promising treatment for dementia

A new study has found a promising new treatment for patients with behavioral variant fronto-temporal dementia, the second most common form of dementia in the under 60s -- resulting in a stabilizing of what would normally be escalating behavioral issues, and a slowing of brain shrinkage due to the disease. It is the second clinical trial to show that the drug, sodium selenate, may slow cognitive decline and neuro-degenerative damage that is the hallmark of many dementias including Alzheimer's Disease.

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Asia and Africa have similar aging burden as the West

Researchers have devised a new metric, the 'Health-Adjusted Dependency Ratio' (HADR) as an alternative to the most commonly used aging metric, the old-age dependency ratio (OADR). The research suggests that age-related health burden is distinct from a ratio based exclusively on age and is the first to incorporate dependency associated with ill-health to generate a new metric that represents a more holistic measure of dependency for 188 countries.

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Recurrent UTIs linked to gut microbiome, chronic inflammation

A study suggests that women who get recurrent urinary tract infections (UTIs) may be caught in a vicious cycle in which antibiotics given to eradicate one infection predispose them to develop another.

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Cutting calories and eating at the right time of day leads to longer life in mice

In a study that followed hundreds of mice over their lifespans, calorie restriction combined with time-restricted eating boosted longevity.

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After Husband Dies 83-Year-old ‘Muddy’ Mildred Runs Her Third Tough Mudder Race to Provide Clean Water

“Muddy” Mildred Wilson is at it again. The 83-year old with two Tough Mudder races to her name just crushed a third one, becoming the oldest person ever to finish the famous 5K. The Tough Muddle 5K in Missouri, Wilson’s home state, was honored to feature the octogenarian for the third time—in this event, she […]

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Higher antioxidant levels linked to lower dementia risk

People with higher levels of antioxidants in their blood may be less likely to develop dementia, according to a new study.

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Fecal transplants reverse hallmarks of aging

In the search for eternal youth, fecal transplants may seem like an unlikely way to reverse the aging process. However, scientists have provided evidence, from research in mice, that transplanting fecal microbiota from young into old mice can reverse hallmarks of aging in the gut, eyes, and brain. In the reverse experiment, microbes from aged mice induced inflammation in the brain of young recipients and depleted a key protein required for normal vision. These findings show that gut microbes play a role in the regulating some of the detrimental effects of ageing and open up the possibility of gut microbe-based therapies to combat decline in later life.

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Study preserves memory in mice, offering promising new basis for active immunization against Alzheimer's disease

During experiments in animal models, researchers have discovered a possible new approach to immunization against Alzheimer's disease. Their method uses a recombinant methionine (Met)-rich protein derived from corn that was then oxidized in vitro to produce the antigen: methionine sulfoxide (MetO)-rich protein.

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Study of promising Alzheimer's marker in blood prompts warning about brain-boosting supplements

Elevated levels of an enzyme called PHGDH in the blood of older adults could be an early warning sign of Alzheimer's disease. Researchers have consistently found high levels of PHGDH expression in brain tissue and blood samples of older adults with different stages of the disease.

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Photographer Records the Moment a Giant Jellyfish Floats Beneath Paddleboarder

An underwater photographer has captured this picture of a large jellyfish under a paddleboarder. The image was taken by photographer and film-maker Lewis Jefferies off Falmouth in  Cornwall It features Lewis’s partner, Sammy, paddleboarding above a compass jellyfish with the sunshine beaming from behind her. “The jellyfish make great subjects to photograph and are quite handy […]

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With His Handmade Bowl, this 12-Year-old Raised $325,000 for Ukrainian Kids

After a young boy’s woodworking project went viral, he seized on his new internet following to raise money—not for himself—but for the children of Ukraine. The power of a viral social media post never ceases to astound. When Gabriel Clarkie’s proud dad tweeted a link to his son’s hobby, carving wooden bowls and posting them […]

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Older men with high body-mass index have more sperm cell irregularities

Single-cell analysis of autopsied human testes suggests that abnormalities associated with aging sperm cells might be exacerbated by elevated body mass index (BMI).

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New article outlines the characteristics of a 'longevity diet'

In a new article, researchers describe the 'longevity diet,' a multi-pillar approach based on studies of various aspects of diet, from food composition and calorie intake to the length and frequency of fasting periods.

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