Scientists discover anti-inflammatory molecules that decline in the aging brain

Scientists reveal another factor implicated in the aging process -- a class of lipids called SGDGs (3-sulfogalactosyl diacylglycerols) that decline in the brain with age and may have anti-inflammatory effects. The research helps unravel the molecular basis of brain aging, reveals new mechanisms underlying age-related neurological diseases, and offers future opportunities for therapeutic intervention.

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Stunning Ancient Artwork Found at Site Sacked by ISIS –Assyrian War Plans Not Seen For 2,600 Years

In April, archeologists working in the ancient Assyrian city of Nineveh which had been destroyed by the Islamic State, uncovered a pulse-quickening discovery—a sealed gateway unknown in any previous excavations or surveys of the site. Carefully opening the door, the archeologists’ eyes fell on a hallway lined with dust that had not been disturbed for […]

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Spend the Night in a Giant Flower Pot – AirBnb is Funding The Most Off-Beat Lodgings

Would you ditch the Courtyard Marriot in order to sleep inside a giant flower pot? What about a nuclear missile bunker, a giant triceratops skull, or a pig sleeping under a quilt of grass and flowers? These are just some of the ideas that came out of the $10 million OMG! Fund from AirBnB, a […]

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Watch How Adult Elephants React to Birth in the Herd Just Moments After Adorable Baby is Born

For the first time in 8 years, the orphan-elephant heard in Kenya’s Sheldrick Wildlife Trust is welcoming a new infant, and the response was inspiring to witness. All elephants celebrate a new baby with great fanfare, but Sheldrick’s herd of former orphans took it to the next level. It has become a time-honored tradition for […]

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50-Year White House Groundskeeper is Surprised With Elm Tree Planted To Honor Him For 200 Years

Presidents come and go from these grounds outside the White House, but the beloved members of their staff—like Dale Haney—stay behind to serve the next First Family. The Bidens this week surprised this longtime groundskeeper who has cared for the White House Rose Garden, hundreds of trees, and more, for a half century. Befitting Haney’s […]

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Woman Discovers Exact Replica of Grandfather’s WWII Plane and Recreates 1942 Photo Before Getting a Special Ride

An Australian woman got the ride of a lifetime after discovering a replica of her grandfather’s World War II plane—and traveling 9,000 miles to recreate her favorite photo. Courtney Dohnt was never able to meet her Australian grandfather who fought alongside the Brits and Allied Forces, flying in a Hawker Hurricane. The plane—called Pegs after […]

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Cellular housekeeping process implicated in fatal neurological disorder

A study shows that as patients age, Huntington's disease impairs autophagy, which eliminates waste from cells. This housekeeping is significant in Huntington's because a buildup of waste in a specific kind of neuron leads to such cells' untimely deaths. The researchers also showed that enhancing the autophagy pathway in such neurons that were created from skin cells of Huntington's patients protects those cells from dying.

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New study expands range of potential Alzheimer's drugs

Alzheimer's disease is associated with a reduction of insulin receptors in brain microvessels, which may contribute to brain insulin resistance and the formation of amyloid plaques, one of the disease's hallmarks. The findings could affect the search for new Alzheimer's drugs.

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High Schooler Self-Publishes Fantasy Novel Over COVID Lockdowns to Distract Him From Video Games

Trying to distract himself from his PlayStation during COVID lockdowns, a London high schooler self-published a fantasy novel that’s now selling as far away as Australia. 16-year-old Dylan Brennan started writing Noble: Betrayed in April 2020, after recognizing he was spending too much time playing video games. The aspiring lawyer said he had long dreamt of […]

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Best evidence yet that lowering blood pressure can prevent dementia

A global study of over 28,000 people has provided the strongest evidence to date that lowering blood pressure in later life can cut the risk of dementia.

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One in 10 older Americans has dementia

In the first nationally representative study of cognitive impairment prevalence in more than 20 years, researchers found almost 10% of older adults have dementia and 22% have mild cognitive impairment.

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Billionaire MacKenzie Scott Donates $15m to Provide Glasses to Farmers With Blurry Vision in Developing Nations

Jeff Bezos’ former wife MacKenzie Scott has donated $15 million to provide hundreds of thousands of people with eyeglasses. It’s believed to be the largest private donation towards assisting uncorrected blurry vision, and will help mainly low-income tea, coffee, cocoa and artisan workers in India, Bangladesh, Ghana, Kenya and Uganda. While it might not be […]

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Young Girls Who Met on a Ship Sailing for America 75 Years Ago are Reunited: ‘I could never forget her’

It’s not uncommon for reunions to take place within a few years of the initial event—or maybe ten to twenty years after the first meeting. But a reunion after 75 years is truly astounding. That’s exactly what took place recently between immigrants Lena and Yolanda, who were young girls when they first met during a […]

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She Built a $15,000 Cottage in the Back Yard For a Brother With Autism: ‘The change has been incredible’

A woman built her brother a little house in her back garden and says it’s been a “game-changer” to give him the independence he needs. Tiffany Chou moved back to Hawaii from New York City to look after her 33-year-old brother, who has autism, after hearing that he was unhappy in his residential home. The […]

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Dwayne Johnson Surprises ‘Real-life Hero’ and Brings Him on TV to Honor His Services

An opportunity to meet Dwayne “The Rock” Johnson is a once-in-a-lifetime moment, but charity-superhero Yuri Williams got so much more than just a handshake when The Rock decided he wanted to do something special for him. Soon to hit the silver screen as a superhero himself, The Rock surprised Yuri on live TV, brought him […]

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Towering Statue Unveiled in London to Honor a National Hero You’ve Probably Never Heard of

Alongside Captain James Cook or Winston Churchill, a new statue in London’s iconic Southbank honors a British hero is not likely known, even by the British themselves. Unsung hero Jo Newby, 52, stands at Southbank in recognition of efforts in the child foster care system and youth special needs soccer. The statue was commissioned by […]

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Manipulating stress response in cells could help slow down aging

Scientists have found that a stress response in cells, when 'switched on' at a post-reproductive age, could be the key to slow down ageing and promote longevity.

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Novel PET imaging agent detects earliest signs of Alzheimer's disease

A new highly selective PET imaging agent can detect the presence of overexpressed monoamine oxidase-B (MAO-B) in cognitively unimpaired individuals with high beta amyloid -one of the earliest signs of Alzheimer's diseas-according to new research. The radiotracer, 18F-SMBT-1, allows for a better understanding of the role of inflammation in Alzheimer's disease, which can enable more accurate staging and prognosis at earlier stages.

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Weight change in early Parkinson's may be tied to changes in thinking skills

People who gain or lose weight soon after being diagnosed with Parkinson's disease may be more likely to have changes in their thinking skills than people who maintain their weight, according to a new study.

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Five hours' sleep a night linked to higher risk of multiple diseases

Getting less than five hours of sleep in mid-to-late life could be linked to an increased risk of developing at least two chronic diseases, finds a new study.

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Individualized fingerprints from sleep brainwaves provide a powerful new tool for understanding disease

A team led by researchers has developed a powerful computational tool for understanding brain health and disease, providing an enhanced way of characterizing the activity of the brain during sleep.

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275 Rare Parrots Saved From Hurricane at Florida Sanctuary: ‘They’re Family’

275 exotic parrots are now on their way to a new wildlife sanctuary after their heroic caretaker pulled all of them up into his stilted house like Noah’s Ark to ride out Hurricane Ian. There’s no question in Will Peratino’s mind that if he had not done so, the waves which crested his 5-foot high […]

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Brain discovery holds key to boosting body's ability to fight Alzheimer's, MS

Researchers have discovered a molecule in the brain responsible for orchestrating the immune system's responses to Alzheimer's disease and multiple sclerosis (MS), potentially allowing doctors to supercharge the body's ability to fight those and other devastating neurological diseases.

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Kindhearted Boy Used His Birthday Money to Start a Food Bank in His Garden Shed

A kind-hearted 11-year-old boy used his own birthday money to launch a foodbank service which he runs from his garden shed. Isaac Winfield fills bags of groceries which have been donated and hands them out to the needy around his hometown. Since starting the foodbank in 2020, the service has grown so much that Isaac’s […]

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He Taught Parents How to Play Drums and Bass So he’d Have People to Jam With–Now They Have Album–WATCH

A New Zealander taught both his parents how to play the drums and the bass so he would have people to jam with—and now they have an album out. Ryan Stokes couldn’t have his friends over to jam during lockdown so he decided to teach his parents how to play instruments. Inspired by The White […]

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Model demonstrates how RNA splicing defects contribute to Alzheimer's disease

Scientists have created a model to study the role of RNA splicing defects in Alzheimer's disease, revealing degeneration and toxicity caused by neuron hyperexcitability.

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Clusters of genes help mice live longer

Researchers have announced the discovery of multiple candidate genes that influence longevity. The discovery of genetic loci that influence longevity only in females is interesting and important, according to the researchers. Genetic loci are clusters of between 10 and 100 genes.

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Scientists detect dementia signs as early as nine years ahead of diagnosis

Scientists have shown that it is possible to spot signs of brain impairment in patients as early as nine years before they receive a diagnosis for one of a number of dementia-related diseases. The team analyzed data from the UK Biobank and found impairment in several areas, such as problem solving and number recall, across a range of conditions.

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Does the Mediterranean diet really decrease your risk of dementia?

A number of studies have suggested that eating a healthy diet may reduce a person's risk of dementia, but a new study has found that two diets including the Mediterranean diet are not linked to a reduced risk of dementia.

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Scientists shed light on COVID-19 booster dose effectiveness among the elderly in Japan

Vaccines against COVID-19 induce the immune system to produce neutralizing antibodies, and boosters ensure their continued production. Researchers from Japan now report that their elderly population produced a very low antibody titer when compared with the younger cohorts. They used a unique fingertip blood collection method to analyze whole blood for circulating antibodies against SARS-CoV-2. The researchers also propose a triage system to address the elderly patients with poor or low post-booster immune response.

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How a Tiny Injured Cat Kickstarted an Entire Sustainability Initiative

It’s so easy to pantomime corporations as mass polluters of the environment, but they’re run by humans, who reacted exactly as anyone else would when they saw a picture of Munchkin the orange Tabby. The stray kitten was taken in by rescuers after it was found with a plastic packaging ring from a Munchkin “Any […]

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Study explores links between people taking multiple medications and dementia diagnosis

A study has provided an in-depth exploration of the links between evolving polypharmacy -- which involves a patient being prescribed more than one drug at any given time -- and a dementia diagnosis.

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Healthy aging requires an understanding of personality types

New research shows that older adults may be better supported as they age when their personalities are considered -- for example, are they more like orchids or dandelions? Researchers examined the potential effects of lifestyle activities on the cognitive health of more than 3,500 adults aged 60+, and found that personality -- using psychology's orchid-dandelion metaphor -- can be a factor in how well supportive programs work.

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Blood levels of 'free range' DNA may signal early detection of dementia and frailty

In a long-term prospective study of more than 600 older participants, researchers say they have evidence that higher levels of cell-free DNA circulating in the blood may signal increased risk of chronic inflammation associated with early signs of frailty and dementia.

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She Finally Met Her Long Lost Dad, Who Didn’t Know She Existed, Thanks to Stranger on Facebook

A woman finally met her long-lost dad, a man who didn’t even know she existed—thanks to an amateur sleuth she met on Facebook. Adrieanna Tyler thought she knew her father until the age of 13, when she overheard him referring to her as his stepdaughter. Since then, she wanted to know who her biological father […]

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Youth Given 8 Months to Live Has Beaten Aggressive Blood Cancer, Now Inspires Others: ‘You can get through anything’

A young Florida man given just eight months to live has beaten a rare and aggressive blood cancer, after nearly dying multiple times during treatments. Now he is inspiring others who are going through health hardships. Michael Cramer went to see a doctor after suffering fatigue, night sweats, and weight loss—symptoms he thought were caused […]

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Novel treatment effective for bladder cancer, study in mice shows

An epigenetics drug currently being used for the treatment of blood cancers and rare sarcomas can stop the growth of bladder cancer by activating the immune system, reports a new study in mice. The drug is now being tested in a national clinical trial for patients with late-stage bladder cancer.

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Age vs. genetics: Which is more important for determining how we age?

Our genetics, the environment and our age all play important roles in our health, but which of these is the most important? A new study suggests that in many cases, age plays a more important role than genetics in determining which genes in our bodies are turned on or off, influencing our susceptibility to disease.

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Detecting Alzheimer's disease from blood samples

Researchers have developed a method to detect build-up of amyloid beta in the brain, a characteristic of Alzheimer's disease, from biomarkers in blood samples.

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Ukraine Girl Bereft Without Her Cat is Reunited Thanks to Kind Strangers in 5 Countries and 7,000 Miles–WATCH

A truly astonishing story of war-time goodwill to mend a 10-year-old’s broken heart will bring a tear to almost anyone’s eyes. Nearly a dozen people, most of whom never met little Agnessa, all took turns helping to get her cat Arsenii travel-ready, out of Ukraine, across Europe, across the Atlantic Ocean, and all the way […]

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Schizophrenia may increase dementia risk by 2.5 times

People with psychotic disorders such as schizophrenia are 2.5 times more likely than those without a psychotic disorder to eventually develop dementia, according to a new review.

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Study links omega-3s to improved brain structure, cognition at midlife

Healthy study volunteers whose red blood cells contained higher concentrations of omega-3 fatty acids were found to have better brain structure and cognitive function in middle age.

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Scientists discover dual-function messenger RNA

A new study has discovered an unprecedented pathway producing telomerase RNA from a protein-coding messenger RNA (mRNA).

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New study underscores need for COVID-19 booster shots for older adults

In a study of more than 80 men and women from Baltimore, Maryland, researchers have added to evidence that COVID-19 booster shots are essential for maintaining long-term immunity against infection, particularly among older adults.

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Decreased proteins, not amyloid plaques, tied to Alzheimer's disease

New research supports the hypothesis that Alzheimer's disease is caused by a decline in levels of a protein called amyloid-beta.

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Mouse study explores Alzheimer's link to the X chromosome

Evidence in mice and human brain tissue reveals a mechanism that may explain the sex-based differences in Alzheimer's disease, including why females are more vulnerable. Researchers report that female brains show higher expression of an X-linked enzyme called ubiquitin-specific peptidase 11 (USP11) compared to males, resulting in greater accumulation of a protein called tau.

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Retiring increases amount of sleep and decreases physical activity

Researchers used accelerometers to study how the 24-hour movement behaviors, i.e. sleep, sedentary behavior, light physical activity and moderate-to-vigorous physical activity change in relation to each other when a person retires. The results show an increase in the amount of sleep, which contributed to decreased amount of physical activity.

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Lonely 67-Year-Old Sets Up Woodworking ‘Shed’ to Combat Loneliness in Men, Following World Trend

Across the English speaking world, men are learning that the easiest way to cure a bout of social isolation is not by talking face to face, but shoulder to shoulder. When Phillip Jackson moved back to England from Australia, he was 67, and immediately felt like a stray dog in his native town of Barnsley. […]

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Role of genomic changes in specific brain cells in Alzheimer's disease

A large study has looked at DNA methylation in Alzheimer's disease. DNA methylation is the process by which the activity of genes is regulated, acting a bit like a dimmer-switch to turn genes on or off. Increasingly, this process is thought to have a key role in the development of diseases such as dementia.

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Biomarkers used to track benefits of anti-aging therapies can be misleading, suggests nematode study

Researchers followed the birth and death of tens of thousands of nematode worms using the 'Lifespan Machine', which collects lifespan data at unprecedented statistical resolution. They found that worms have at least two distinct 'biological ages', and that these have consistent correlations between each other, suggesting the existence of an invisible hierarchical structure that regulates the ageing process. The findings challenge the idea of living organisms having a single, universal biological age. It also means mean that biomarkers used to assess biological age can be changed by interventions such as diet, exercise, or drug treatments without actually turning a 'fast ager' into a 'slow ager'. The study calls into question the use of ageing biomarkers -- what exactly are they measuring?

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Young women who reduce binge drinking could decrease risk of COVID-19 infection, study shows

New research correlates substance-use patterns and personal characteristics with COVID-19 impacts.

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SuperAger brains contain 'super neurons'

Neurons in an area of the brain responsible for memory were significantly larger in SuperAgers compared to cognitively average peers, individuals with early-stage Alzheimer's disease and even individuals 20 to 30 years younger than SuperAgers -- who are aged 80 years and older, reports a new study. The study of was the first to show that these individuals carry a unique biological signature that comprises larger and healthier neurons in the entorhinal cortex that are relatively void of tau tangles.

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He Finally Located Source of Mysterious Sound–A New Frog Species Named After His Rewilding Quest in Costa Rica

A nature-lover’s well-trained ears led to the discovery of a new species of frog, after the Costa Rican man searched for six months to find the source of a mysterious sound. The tiny green frog was discovered by Donald Valera Soto, a naturalist and co-owner of Tapir Valley Nature Reserve, a cattle ranch that he […]

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