The Top 10 Acts of Kindness in 2022 Warmed Our Hearts and Restored Our Faith in Strangers and Neighbors

An act of kindness is like lighting a candle in a dark room, reminding everyone that such a point of light will always penetrate the darkness. They happen every day all over the world for a variety of reasons, and while they don’t always make headlines, they do make heartlines—and these ten stories are like […]

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New Evidence Unearthed by Podcasters Frees 2 Men Wrongfully Imprisoned for 25 Years

Two men wrongfully-imprisoned for more than two decades were able to spend Christmas with their families after a podcast and non-profit advanced evidence of their innocence. Darrell Lee Clark and Cain Joshua Storey were just teenagers when they stood trial for a murder of their 15-year-old friend he died of gunshot wounds at a party […]

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Multi-institutional collaboration unveiling the mysteries of senescent cells and their effect on aging and human health

Researchers are bridging mouse and human data to reveal the biology of senescent cells. Senescent cells stop dividing in response to stressors and seemingly have a role to play in human health and the aging process. Recent research with mice suggests that clearing senescent cells delays the onset of age-related dysfunction and disease as well as all-cause mortality. 

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Enzyme that protects against viruses could fuel cancer evolution

An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a new study. The finding suggests that the enzyme may be a potential target for future cancer treatments.

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New biomarker test can detect Alzheimer's neurodegeneration in blood

The biomarker, called 'brain-derived tau,' or BD-tau, outperforms current blood diagnostic tests used to detect Alzheimer's-related neurodegeneration clinically. It is specific to Alzheimer's disease and correlates well with Alzheimer's neurodegeneration biomarkers in the cerebrospinal fluid. Scientists hope that monitoring blood levels of BD-tau could facilitate screening and enrollment of patients from populations that historically haven't been included in research cohorts.

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Care Home Residents Surprised By Festive Penguins Bringing Christmas Cheer

Residents of a senior home got a flippin’ good surprise last week, after two charming feathered guests arrived to deliver some Christmas cheer. Seniors at the Colne View facility in Halstead, Essex, woke up to find two penguins outside. Accompanied by introductions using their adorable names, Pringle and Widget waddled through the halls, exploring the […]

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People sleep the least from early 30s to early 50s

People sleep less in mid-adulthood than they do in early and late adulthood, finds a new study.

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Can the AI driving ChatGPT help to detect early signs of Alzheimer's disease?

The artificial intelligence algorithms behind the chatbot program ChatGPT -- which has drawn attention for its ability to generate humanlike written responses to some of the most creative queries -- might one day be able to help doctors detect Alzheimer's Disease in its early stages. Research recently demonstrated that OpenAI's GPT-3 program can identify clues from spontaneous speech that are 80% accurate in predicting the early stages of dementia.

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Ottawa Nurse Wins $100,000 Cash From Radio Station–Watch Her Thrilling Reaction

A radio station in Canada surprised a nurse with the best holiday gift of her life. The young mother of two—with a third child on the way—heard the news through her phone while a colleague captured her reaction on video. The station in Ottawa known as Hot 89.9 chose Nicole as their Guaranteed Giveaway winner […]

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50 Years Ago, Apollo Crew Gave Humanity a Christmas Gift: Our First Gaze at ‘the Blue Marble’ Still Inspiring us Today

The astronauts of the Apollo 17 mission left a Christmas gift under the tree for all of humanity as they traveled on their way to the Moon. “The Blue Marble” is still one of the most inspiring images of our Earth ever taken, and it was 50 years ago on Christmas Eve that they did […]

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Smoking increases chances of mid-life memory loss, confusion

Middle-aged smokers are far more likely to report having memory loss and confusion than nonsmokers, and the likelihood of cognitive decline is lower for those who have quit, even recently, a new study has found.

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Characterizing rare, damaged cells that block functions of neighboring healthy cells

Senescent cells, which emerge after tissue injury, create an aged-like inflamed microenvironment that is negative for stem cell function and tissue repair. The finding provides a basis for mitigating the loss of muscle regenerative capacity in elderly people and for improving muscle repair in young healthy people.

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Man Spells Out ‘Hi Kevin’ in Lights for 20 Years–to Honor His Neighbor

Every Christmas, Mike Witmer gets out his colored lights to weave a very specific message out into the night. Witmer says passersby are sometimes confused by his lights, which read ‘Hi Kevin’ across his roof, but it’s to honor the memory of a young boy who passed away from cancer in 2010. For the past […]

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Head trauma, PTSD may increase genetic variant's impact on Alzheimer's risk

Researchers concluded that PTSD, TBI, and a specific variant of the APOE gene showed strong associations with Alzheimer's Disease and related dementias (ADRD).

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Digital detection of dementia: Using AI to identify undiagnosed dementia

Rising to meet the formidable challenge of the timely diagnosis of dementia, research scientists are conducting the Digital Detection of Dementia study, a real-world evaluation of the use of an artificial intelligence (AI) tool they developed for early identification of Alzheimer's disease and related dementias in primary care, the setting where most adults receive healthcare. Individuals identified as cognitively impaired will be referred for diagnostic services.

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Cognitively impaired degu is a natural animal model well suited for Alzheimer's research

A new study reveals that a long-lived Chilean rodent, called Octodon degus (degu), is a useful and practical model of natural sporadic Alzheimer's Disease.

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From Messi to Morocco: 5 Good News Stories From a Memorable World Cup

From Messi’s twilight triumph to bountiful showings of hospitality by the Qatari people, there was plenty to smile about during this year’s World Cup. As the curtain came down on the 2022 FIFA World Cup in Qatar, most fans of the sport will immediately look forward to enjoying the return of the domestic leagues, which […]

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Woman Who Hated Exercise Starts Lifting Weights to Help Combat Arthritis–And is Now a Regional Gold Medalist

A woman who hated exercise took up powerlifting to help combat her arthritis and is now slaying it as a commonwealth gold medalist in the sport. She says she’s now fitter than when she was in her 20s, and has now won gold, silver, and bronze medals in weightlifting. Arthritis prevented 58-year-old Kelly Clark from […]

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Patterns of lifespan weight gain/loss may predict dementia risk

Dementia is a growing global public health concern currently affecting 50 million people and is expected to rise dramatically to more than 150 million cases worldwide by 2050. Obesity, commonly measured by body mass index (BMI), continues to be a global epidemic and earlier studies suggested that obesity at midlife may lead to increased risk for dementia. But the association between BMI and the risk of dementia remains unclear. Now, researchers have found that different patterns of BMI changes over one's life course may be an indicator of a person's risk for dementia.

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Heartwarming Moment Ex-Foster Kid Asks to Be Adopted by Family He Sold a Car To

There’s no substituting the need for family, and one young man raised in the foster care system hoped to find one in a pair of perspective car buyers he met last year. Video shows the Wilkinsons family, who walked off the lot with a car and a new friend in April 2021, reacting tearfully to […]

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Looking for an early sign of LATE

Researchers provide new insights into the pathology of limbic predominate age-related TDP-43 encephalopathy, which mimics Alzheimer's, making it very difficult to identify in living patients.

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Captain Tom Moore’s Family Launches Online Bulletin Board Where Strangers Share Favorite Moments of Kindness

During the first COVID-19 lockdowns in England the late army captain, 99-year-old Sir Tom Moore, attempted to raise money for NHS Charities Together by walking across his garden 100 times. Now, believing that people need more positive and hopeful news in their life, his family is following in his footsteps by launching a Christmas campaign […]

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Strong connection to neighbors may improve health outcomes

Strong neighborhood connections reduced the negative impact of living alone on the death rates of older Chinese Americans, according to new researchers.

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Olfactory viral inflammation associated with accelerated onset of Alzheimer's disease

Viruses can inflame and disrupt connections between the olfactory system, which governs the sense of smell, and the part of the brain associated with memory and learning, possibly accelerating the onset of Alzheimer's disease, according to a new study.

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Employee Immediately Gives Her Favorite Shoes to Man Walking With Boxes on his Feet

The manager of a Minnesota liquor store was surprised to come back from lunch yesterday to find his counterhelp walking around in her socks. That’s because security camera footage revealed she had just given her favorite shoes—a pair of purple retro Jordans, to a homeless man she saw strapping boxes to his feet. Brooklyn Center […]

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Longevity treatments do not slow aging

Three approaches with a reputation for slowing aging processes have proven largely ineffective. For their study, researchers developed a new method to measure aging, which accounts for the complexity of aging in organisms.

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New immune culprit discovered in Alzheimer's disease

Cerebrospinal fluid, the brain's immune system, becomes dysregulated as we age and plays a newly discovered role in cognitive impairment in diseases such as Alzheimer's, a new study has found.

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Exercise, mindfulness don't appear to boost cognitive function in older adults

For decades, doctors and scientists have known that exercise is important for older adults -- it can lower risk for cardiac issues, strengthen bones, improve mood and provide other benefits. Likewise, mindfulness training reduces stress, and stress can be bad for the brain, so many have thought that exercise and/or mindfulness training might improve brain function. In a large study, researchers had hypothesized that if older adults exercised regularly, practiced mindfulness or did both, there might be cognitive benefits -- but that's not what they found.

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One-Armed Basketball Player Recruited for College Team Scores His First Points

On December 10th, teammates and fans of Northwestern State sounded their applause when their new freshmen basketball player scored his first points for the team. It was an extra special applause for the point guard, since Hansel Emmanuel has only one arm. A minute later he added to his total with a thunderous dunk in […]

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Who is more prone to recurrent UTIs? Bladder bacteria may be key

Researchers have identified specific bacteria in the bladder that may indicate which postmenopausal women are more susceptible to recurrent urinary tract infections (UTIs), and they found that estrogen may play a role in reducing that susceptibility.

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Frightening Relative of T-Rex is Discovered and Might be ‘Missing Link’ in Tyrannosaur Evolution

An evolutionary “missing link” species was just discovered, and it was a very big and scary link in a very big and famous chain. The newfound species, Daspletosaurus wilsoni, is thought to be the direct ancestor of Tyrannosaurus Rex, and had a unique set of facial features like a set of ridges called “hornlets” above its eye socket. […]

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Aging is driven by unbalanced genes

In a new study, researchers used artificial intelligence to analyze data from a wide variety of tissues, collected from humans, mice, rats and killifish. They discovered that the length of genes can explain most molecular-level changes that occur during aging.

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Residents of Tiny Village in Belgium Will be Sharing a Massive Lottery Win, Taking Home $915k Each–Tax Free

In the 1998 comedy Waking Ned Devine, a multi-million dollar lottery jackpot is split between the stunned residents of a tiny Irish village. Well, last week, the film’s storyline became a reality for the small Belgian village of Olmen, near Anterp. 165 Olmen residents divided up an unbelievable $150 million dollars won in the Euromillions […]

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New blood test can detect 'toxic' protein years before Alzheimer's symptoms emerge, study shows

Researchers can detect 'toxic' small aggregates of a particular protein in the blood of individuals with Alzheimer's disease, as well as in individuals who showed no signs of cognitive impairment at the time the blood sample was taken, but who developed it at a later date. This blood test picks up oligomers -- or small, misfolded aggregates -- of the amyloid beta protein, which scientists believe triggers the development of Alzheimer's.

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Estrogen may offer protection against delirium

Delirium is common among women with urinary tract infections (UTIs) -- especially those who have experienced menopause. Investigators, working with laboratory mice, have been able to prevent symptoms of the condition with estrogen, which is commonly used for hormone replacement therapy.

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Strangers Join Together to Rent 15-Passenger Van after Flight was Canceled–Take 10-hour Road Trip Instead

A determined mother’s positive thinking got her daughter home when her flight was canceled by helping to organize other stranded passengers to pitch in for a rental car. Alanah Story was set for a 7:00 PM flight from Orlando to Knoxville when like so many others this year, it was delayed, then canceled. Alanah’s mother […]

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'Sandwich generation' study shows challenges of caring for both kids and aging parents

Their older parents need care. Their kids are still under 18. And they probably have a job, too. They're the 'sandwich generation' -- a longtime nickname for the mostly female, mostly middle-aged group of Americans who serve as caregivers for both older and younger family members at once. A new study estimates there are at least 2.5 million of them, while giving a detailed view into who they are, and which older adults rely on them.

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After Debut Author’s Lonely Book Launch, Stephen King, Neil Gaiman and Margaret Atwood Swoop in With Support

New author Chelsea Banning tweeted to being “a little embarrassed” after the first book signing of her first book was attended by no one but her two friends. A blessing in disguise it was, as her tweet somehow attracted a large crowd of authors ranging from successful to legendary, sharing their own stories of book-signing […]

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Redesigning diabetes technology to detect low blood sugar in older adults with diabetes and Alzheimer's disease

A human factors engineer and health services researcher is developing and testing user-friendly health information tools and technology designed to enhance accessibility and value to older adults with both diabetes and Alzheimer's disease, and their caregivers. Without numerous finger sticks, these tools and technology will be designed to provide patients, caregivers, and clinicians with glucose metrics needed to diagnose hypoglycemia and identify treatment options.

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New study sheds light on how neurons respond to aged-related iron accumulation

A recent study details the neuronal response to excessive iron accumulation, which is associated with age-related neurodegenerative diseases.

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Twin ‘Saved Sister’s Life’ in Womb by Sending Distress Signal Forcing Early Delivery That Uncovered Major Problem

A twin saved her sister’s life while still in the womb, by sending out distress signals prompting doctors to deliver them early—which turned out to be critical for the other twin’s survival. Preemie Poppy McBride’s heart rate began to waver on the monitor at 31 weeks and five days into the pregnancy, which doctors say […]

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Pregnant moms' stress may accelerate cell aging of white, not Black, kids, study finds

Does stress during pregnancy impact children's cell aging, and does race matter? The answer is yes, according to a new study.

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World’s Oldest Pen Pals Turn 100, After 84 Years of Transatlantic Letters–And Now They’re Meeting on Zoom

The world’s oldest pen pals have both turned 100 years old, and are celebrating 80 years of letters sent across the pond. Geoff Banks from Devon, England, and American Celesta Byrne from New Jersey started writing to each other in 1938, when they were just 16-years-old. They were paired by an educational project that sought […]

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Childhood Best Friends Who Lost Touch Reunited 60 Years Later–in a Senior Care Home

Two childhood best friends who were ‘joined at the hip’ as kids were reunited over a half-century later—when they least expected it. Irene Gresty and Janet Henderson were neighbors in the 1940s, growing up in Linlithgow, West Lothian, England, but, like so many friendships, they lost touch over the years. Irene got married and moved […]

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Optimal blood tests for development of new therapies of Alzheimer's disease

A new study have identified which blood tests are best at detecting Alzheimer's disease during the earliest stages, and also other another blood test that are is optimal for detecting relevant treatment effects. These findings will speed up the development of new therapies that can slow down the disease progression.

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Young people make up greater proportion of COVID-19 deaths in 2021 compared to 2020

Since March 2020, COVID-19-related deaths claimed over a million lives in the U.S. alone. In the pandemic's early phases, most deaths were among older adults, but in 2021, deaths in younger persons increased while deaths in older persons decreased. A new study addresses this unexpected shift in COVID-19 mortality to relatively younger Americans and finds an increase in years of life lost due to COVID-19.

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To Help His Neighbors Save on Energy ‘Baker Ed’ Revives the Tradition of the Village Oven—Baking People’s Cakes for Free

A baker in the English town of Guisborough, pop. 17k or thereabouts, is reviving an ancient tradition to help his neighbors endure high energy costs. Thousands of years ago, societies built one oven in town where everyone went to bake their bread, and now Ed Hamilton-Trewhitt from Brickyard Bakery is offering to bake Christmas cakes […]

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How immune cells prevent cognitive decline

Mice altered to prevent the production of a particular type of immune cell struggled to form new memories.

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Early life experiences can have long-lasting impact on genes

Early life experiences can impact the activity of our genes much later on and even affect longevity, finds a new study in fruit flies.

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Socceroos Jumping For Joy After Historic Start to Australia’s Upstart World Cup Campaign

Australia have advanced to the knockout rounds of the World Cup for the first time since 2006, with coach Graham Arnold hailing his boys as a new “golden generation.” They now face a stiff test against one of the tournament favorites in Argentina this Saturday on just three-days rest. It would have been the safest […]

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Researchers identify the role of an Alzheimer's disease risk gene in the brain

A new study links a gene concentrated in the brain’s cleanup cells, known as microglia, to the inflammation that has increasingly emerged as a key mechanism contributing to Alzheimer’s disease. The findings may offer a new potential target for therapies for the intractable condition.

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