Deaf Children Are First Humans to Have Hearing Pathway Restored in Dramatic Demonstration of New Gene Therapy

In China, a true medical breakthrough has been achieved in a human trial that had as many as 10 children born deaf have their hearing restored through a genetic therapy method. MIT hailed it as China’s first domestic gene therapy breakthrough, as well as “the most dramatic restoration of a lost sense yet achieved.” Much […]

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Improving deep sleep may prevent dementia, study finds

As little as 1 per cent reduction in deep sleep per year for people over 60 years of age translates into a 27 per cent increased risk of dementia, according to a study which suggests that enhancing or maintaining deep sleep, also known as slow wave sleep, in older years could stave off dementia.

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‘There’s still beauty’: A National Park Bounces Back After California’s Biggest Single Fire

The Dixie Fire of 2021 was the largest single blaze in California’s history, but even this human-accelerated firestorm couldn’t tamp down the resilience of nature. In August, it devastated Lassen Volcano National Park in Northern California, leaving parts of it reminiscent of “Mordor” yet in a feature piece from The Guardian, it’s clear nature is […]

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Millionaire Builds 99 Tiny Homes to Cut Homelessness in His Community–He Even Provides Jobs On Site for Them

  After selling out for eight figures to a competitor, a New Brunswick entrepreneur is using all that cash to build a community of tiny homes for those who need it most. In the city of Fredericton, his factory is churning out 1 tiny home every 4 business days in a bid to create the […]

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Red Maple Trees Line English Road to Honor 418 Canadian Soldiers Who Died Defending Freedom Overseas

Stunning photos of autumnal red maple trees lining a highway are a moving commemoration to Canadian soldiers who gave their lives overseas during the two World Wars. Many motorists are unaware that they are passing through a sacred war memorial on the A3 in Hampshire, England. The 418 maples, Canada’s national tree, were planted near […]

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Man’s Wedding Ring Lost in Ocean is Found So He Drives 1,600 Miles to Thank Humble Metal Detectorist in Person

A metal detectorist has reunited a man with his diamond wedding ring after uncovering it on a sandy beach. Stephane Seguin lost the ring while swimming on a trip to St Augustine, Florida. The 40-year-old saw detectorist Joseph Cook out searching the sands and asked him to keep an eye-out for his ring. “When I […]

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Debt Activists Cancel $10 Million in Student Loan Debt After Buying it All for a Penny on the Dollar

From Atlanta comes an uplifting story of nearly 3,000 students getting a brighter future after a debtor organization bought $10 million in student loans for the purpose of canceling it. The total cost of the purchase was one-and-a-quarter pennies for every dollar of debt—with the low value reflecting the likelihood of the university in question—Morehouse […]

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A Zoo Is Fighting to Bring Lioness and Her 3 Cubs Abandoned in War-Torn Ukraine to Britain

Zoo animals are always in great danger during wartime, but the Yorkshire Wildlife Park has been working to get a lioness mother and her three cubs from Ukraine’s capital of Kyiv to the safety of their zoo’s sprawling enclosure for months. Safe but not sound, they were transferred from Kyiv to a holding facility in […]

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Top 30 Most Delightful Things That Happen Unexpectedly–Like Finding Cash in Jeans or Compliments from Strangers

A new poll compiled the top 30 most unexpectedly delightful things to happen, including pulling cash from the pocket of an old pair of jeans, getting a surprise refund, and receiving a compliment from a stranger. The survey of 2,000 adults, found 36 percent love it when someone lets them jump the line in a […]

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Local Car Community Comes Together in Two Days to Form Parade of 83 Drivers for Stranger’s Birthday – WATCH

A devoted single mom was looking for a budget friendly way to give her son a special birthday—so she reached out on Facebook to the local car community and their response left her speechless. Mikayla Freeman was hoping to urge a few motor enthusiasts to form ‘a car parade’ down their street near Nashville. “My […]

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Texas Explorer Leads Team to Become the First Ever to Row the Arctic’s Northwest Passage

Described as “one of the last great ‘firsts'” the passage from the Atlantic to the Pacific through the Canadian Arctic was, for the first time ever, rowed by an expedition of 3 men and 1 woman. West Hansen, Eileen Visser, Mark Agnew, and Jeff Wueste, who together styled themselves the “Arctic Cowboys,” set off in […]

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Women with a heart healthy diet in midlife are less likely to report cognitive decline later

Women with diets during middle age designed to lower blood pressure were about 17 percent less likely to report memory loss and other signs of cognitive decline decades later, a new study finds.

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When Builders in Maui Came Together to Help Build Tiny Homes for Man’s Family, it Grew into Growdfunded Rehousing Project

Buried under the 24-hour news cycles of the last few months, recovery in Lahaina is progressing, one tiny house at a time. William Fincher, an owner of two restaurants in the historic Maui town which tragically burned down this August, is receiving help from neighbors and friends to build a pair of tiny homes for […]

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Hero Bus Driver Saves Boy From Choking on Coin, Rushing Him to Safety–WATCH

Not all heroes wear capes, some like Raquel Radford Baker, drive school buses. Baker, a veteran driver for Dallas Independent School District, was on a routine route for the kids at Seagoville North Elementary School when one of them, a boy just 7 years old began to choke. First-grader Preston motioned to Baker that he […]

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Chicago Marathoner Gave Up Record Finish to Save Kitten–Which Goes on to Find New Home with Spectator

A Chicago Marathon runner gave up a record finish in order to save a stray kitten she found on the course. The story got sweeter when amid the spectators on the side of the road, she found Andrea Maldonado who called out that she would give the kitten a new home. Marathoner Sarah Bohan was […]

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Molecular age of the eye determined

A team of researchers have mapped almost 6,000 proteins from different cell types within the eye by analyzing tiny drops of eye fluid that are routinely removed during surgery. The researchers used an AI model to create a 'proteomic clock' from this data that can predict a healthy person's age based on their protein profile. The clock revealed that diseases such as diabetic retinopathy and uveitis cause accelerated aging within specific cell types. Surprisingly, the researchers also detected proteins associated with Parkinson's disease within eye fluid, which they say could offer a pathway to earlier Parkinson's diagnoses.

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Researchers uncover mechanism that links NAD+ to fertility problems

A woman's fertility normally decreases by her late 30s with reproductive function eventually ceasing at menopause. It is known that a small molecule called nicotinamide adenine dinucleotide (NAD+) plays a critical role in this decline, and scientists have revealed how this happens and have identified potential new approaches to enhance reproductive longevity.

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Scientists discover links between Alzheimer's disease and gut microbiota

Research identifies links between gut bacteria, inflammation and brain changes associated with Alzheimer's disease. The findings suggest that Alzheimer's symptoms can be transferred via the gut microbiota.

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Adults with ADHD are at increased risk for developing dementia

Adults with attention-deficit/hyperactivity disorder (ADHD) are nearly three times more likely to develop dementia than adults without ADHD, according to a new study. The study followed more than 100,000 older adults in Israel over 17 years to examine if adults with ADHD are at increased risk for dementia, including Alzheimer's disease.

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Researchers reveal link between Alzheimer's and sex hormones

Researchers have shown female sex hormones play a significant role in how Alzheimer's manifests in the brain. The study also highlights the importance of developing therapeutic strategies focused on these hormonal connections. The research indicates a need to better understand the role of estradiol -- a form of the female sex hormone estrogen, used therapeutically to mitigate menopause symptoms -- in Alzheimer's disease.  

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Fungal infection in the brain produces changes like those seen in Alzheimer's disease

Researchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and, important for the understanding of Alzheimer's disease development, generates amyloid beta (Ab)-like peptides, toxic protein fragments from the amyloid precursor protein that are considered to be at the center of the development of Alzheimer's disease.

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Can't stop binging on fries and BBQ?

People overeat and become overweight for a variety of reasons. The fact that flavorful high-calorie food is often available nearly everywhere at any time doesn't help. Researchers have determined for the first time why certain chemicals in cooked or processed foods, called advanced glycation end products, or AGEs, increase hunger and test our willpower or ability to make healthy choices when it comes to food.

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72-Year-old Graduates from College with His 99-year-old Mom Cheering Him On

Sam Kaplan of Lawrenceville, Georgia has added many items to his resume over the years. But on May 11th, in his 72nd year of life, he added a particularly late line item—a college degree. Alongside classmates 50 years his junior, Kaplan crossed the stage in cap and gown to receive an undergraduate degree in Cinema […]

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Calorie restriction in humans builds strong muscle and stimulates healthy aging genes

Reducing overall calorie intake may rejuvenate your muscles and activate biological pathways important for good health, according to researchers. Decreasing calories without depriving the body of essential vitamins and minerals, known as calorie restriction, has long been known to delay the progression of age-related diseases in animal models. This new study suggests the same biological mechanisms may also apply to humans.

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Minnesota Cat Sanctuary Unveils New Outdoor Playground for Feral Rescues: “People care about them”

Come down and chip in on the farm: the Furball Farm that is. This is the outdoor cat shelter at Furball Farm, in Faribault, Minnesota. The staff and volunteers built this impressive outdoor structure to allow their dozens of feral rescues a place to play and learn to be around humans. Most of the cats […]

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Most accurate test to date developed to measure biological aging

Researchers have developed a new test that can accurately measure biological aging in a clinical setting. The discovery was made while studying patients for the aging effects of chronic kidney disease.

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Look at The Tech and Trouble Taken to Retun Rehabbed Manatees into Home Waters

Eight manatees are por-poised to be released back into the waters of Florida where they were rescued years ago. The graceful sea cows, weighing as much as two Honda civics, were driven to the airport in specialized crates that monitored their conditions. The crates were then loaded into a cargo plane at Cincinnati airport, and […]

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Restoring nerve-muscle connections boosts strength of aging mice, study finds

A drug that boosts strength in injured or aging mice restores connections between nerves and muscle and suggests ways to combat weakness in humans due to aging, injury or disease.

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New study finds link between subjective and objective memory decline

Among people who report memory and thinking problems, some show no signs of a problem on standard tests, while others have subtle declines on their tests. A new study shows that people who have subtle problems with these tests may have an increased risk of developing mild cognitive impairment, which can be a precursor to dementia.

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Certain navigational mistakes could be early signs of Alzheimer's disease

People with early Alzheimer’s disease have difficulty turning when walking, according to a new study using virtual reality.

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Wash. D.C’s ‘Weed Warrior’ Volunteers Tackle ‘Mile-a-Minute’ Invasives to Save the Capital’s Trees

Around the capital beltway or Washington’s famous Rock Creek Park, you may see a group of people ripping up vines along the treeline beside the roads. If you have then you’ve glimpsed superheroes who traded in their capes for gardening gloves and their time for the satisfaction of terminating an invasive species and saving a […]

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Mom and Daughter Reunite as Co-Workers Aboard Hospital with Nurse Who Saved Their Lives 30 Years Ago

30 years and a continent separated Catherine Conteh, her daughter Regina, and a nurse named Aly who was visiting their home in Sierra Leone and saved her life by funding an emergency surgery. Regina wasn’t born on the day of that fateful meeting, technically, because Catherine was dying after four days in labor. Unable to […]

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Cancer drug restores immune system's ability to fight tumors

Cancers that have a deletion in the 9p21 section of their genomes tend to have worse outcomes for patients and increased resistance to immunotherapy. A new, bio-inspired drug restores the effectiveness of immune cells in fighting cancer. In mouse models of melanoma, bladder cancer, leukemia and colon cancer, the drug slows the growth of tumors, extends lifespan and boosts the efficacy of immunotherapy.

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Dad’s Love Letter to a Small Town Public Library

A Massachusetts man wrote a love letter that was published in his local newspaper, the Salem Evening News, in late August—but it wasn’t your normal love letter. As a stay-at-home Dad to two young children, Sean Devlin soon learned that the historical downtown library (which opened in 1913) had a fantastic children’s program. “I personally […]

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Protein that could help defeat Alzheimer's and increase productive lifespan

Alzheimer’s disease is the most common type of dementia, a disorder of progressively worsening memory and other thinking abilities. It rose up in the ranks of leading causes of death over the past several decades. It can also limit the duration of a working career, create uncertainty in the financial planning for retirement and rob patients of enjoyment and happiness in the final years. An effective treatment against this disease could give back to the patient the decision when to retire and improve quality of life in advanced age.   Now, scientists are on the trail of a promising new therapeutic target – ABCA7, a protein known to protect from Alzheimer’s disease. The study uncovers new information about the relationship between ABCA7, cholesterol, and inflammation in human brain cells.

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New findings pave the way for hearing loss therapies

As we age, many of us will eventually need hearing aids. In some cases, the reason for this may be a signaling pathway that controls auditory sensory cell function and is downregulated with age.

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24 Prison Inmates Get College Degrees, Graduate Together Thanks to UC Program: ‘I literally feel free’

In California, prison inmates are preparing to make their second chance count by studying towards a college degree while incarcerated. Yesterday, 24 inmates in caps and gowns at the Richard J. Donovan Correctional Facility in San Diego graduated with associates degrees in sociology and liberal arts before a ceremony honoring their commitments. The degrees were […]

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Strong link between ADHD and car crashes in older adult drivers

In a study on the prevalence of attention-deficit/hyperactivity disorder (ADHD) and its association with crash risk among older adult drivers, researchers found that older adult drivers with ADHD are at a significantly elevated crash risk compared with their counterparts without ADHD. Outcomes included hard- braking events, and self-reported traffic ticket events, and vehicular crashes. Until now research on ADHD and driving safety was largely limited to children and young adults, and few studies assessed the association of ADHD with crash risk among older adults.

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Selective removal of aging cells opens new possibilities for treating age-related diseases

A research team has achieved a significant breakthrough in the treatment of age-related diseases. This groundbreaking development is set to redefine the future of healthcare and usher in a new era of targeted therapeutic interventions.

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Graphene oxide reduces the toxicity of Alzheimer's proteins

A probable early driver of Alzheimer's disease is the accumulation of molecules called amyloid peptides. These cause cell death, and are commonly found in the brains of Alzheimer’s patients. Researchers have now shown that yeast cells that accumulate these misfolded amyloid peptides can recover after being treated with graphene oxide nanoflakes.

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New strategy for eye condition could replace injections with eyedrops

A new compound potentially could offer an alternative to injections for the millions of people who suffer from an eye condition that causes blindness.

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They Accidentally Bought a Run-Down 120-yo House in Scotland–But Decided to Restore it With Love After Whoopsie Auction (LOOK)

Some people enjoy the thrill of a blind auction, but you probably wouldn’t be comfortable buying anything other than a record collection or some home furnishings. For a young cross-Atlantic couple in their 20s, they found themselves the proud owners of a dilapidated, crumbling, rural Scottish home after their best-laid plans “gang agley.” Believing he […]

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3 Cooks in Prison Honed Creativity with Drab Ingredients–Now Out, Award-Winning Chef And Businessmen

“There are geniuses in there,” said 2-time James Beard Award winner, Keith Corbin, referring to incarcerated men and their ability to cook with the most lifeless, flavorless ingredients imaginable. Corbin spent 10 years in prison himself, and combined with his career as an award-winning chef at his restaurant Alta Adams, he knows what it takes […]

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Blocking abnormal stem cell signal during aging lessens related bone loss

A cellular signal essential to development of the skeleton increases abnormally during aging to weaken bones.

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Plant chloroplasts promise potential therapy for Huntington's disease

A chloroplast enzyme safeguards plants against pathological protein aggregation that causes Huntington’s and other neurodegenerative diseases. New research may have found a way to 'copy' the mechanism for application in human cells.

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Starbucks Workers Raise Over $40K for Beloved Barista After Her Car Was Burglarized

Recently, hordes of West Virginia college kids who “couldn’t afford a cup of coffee” shelled out five dollars to help a motherly Starbucks barista buy a new car. The Starbucks on the Marshall University Campus in Huntington, West Virginia, was always like a small family with Karen Collinsworth, 65, at the head of the table. […]

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Caribbean Island Designated a Huge Nature Reserve After Complete Eradication of Rats Brought Nature Back in Balance

Redonda, a Caribbean island of small repute, has undergone a dramatic transformation from a barren wasteland of goats and rats, to a pristine, re-wilded nesting spot for many seabirds and endangered plants. It’s one of many remote islands around the world’s seas that, with a helping hand, have rid themselves of invasive animals and plants […]

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Decoding the complexity of Alzheimer's disease

Using more than 2 million cells from over 400 postmortem brain samples, researchers performed the largest-scale analysis of the genomic, epigenomic, and transcriptomic changes that occur in every cell type in the brains of Alzheimer's patients.

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Is a longer reproductive lifespan good for your brain?

People with a higher cumulative estrogen exposure throughout their life may have a lower risk of cerebral small vessel disease, according to a new study.

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Novel tau PET tracer exhibits high sensitivity and specificity, allowing for earlier identification of Alzheimer's disease

A new tau PET radiotracer, 18F-SNFT-1, has been found to be more effective than existing tau PET radiotracers in identifying Alzheimer’s disease in its earliest stages, according to research. In a head-to-head comparison, 18F-SNFT-1 possessed preferable brain pharmacokinetics and demonstrated higher affinity and selectivity for Alzheimer’s tau lesions compared to clinically used second-generation tau PET tracers.

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