The Top 10 Acts of Kindness in 2022 Warmed Our Hearts and Restored Our Faith in Strangers and Neighbors

An act of kindness is like lighting a candle in a dark room, reminding everyone that such a point of light will always penetrate the darkness. They happen every day all over the world for a variety of reasons, and while they don’t always make headlines, they do make heartlines—and these ten stories are like […]

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New Evidence Unearthed by Podcasters Frees 2 Men Wrongfully Imprisoned for 25 Years

Two men wrongfully-imprisoned for more than two decades were able to spend Christmas with their families after a podcast and non-profit advanced evidence of their innocence. Darrell Lee Clark and Cain Joshua Storey were just teenagers when they stood trial for a murder of their 15-year-old friend he died of gunshot wounds at a party […]

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Multi-institutional collaboration unveiling the mysteries of senescent cells and their effect on aging and human health

Researchers are bridging mouse and human data to reveal the biology of senescent cells. Senescent cells stop dividing in response to stressors and seemingly have a role to play in human health and the aging process. Recent research with mice suggests that clearing senescent cells delays the onset of age-related dysfunction and disease as well as all-cause mortality. 

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Enzyme that protects against viruses could fuel cancer evolution

An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a new study. The finding suggests that the enzyme may be a potential target for future cancer treatments.

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New biomarker test can detect Alzheimer's neurodegeneration in blood

The biomarker, called 'brain-derived tau,' or BD-tau, outperforms current blood diagnostic tests used to detect Alzheimer's-related neurodegeneration clinically. It is specific to Alzheimer's disease and correlates well with Alzheimer's neurodegeneration biomarkers in the cerebrospinal fluid. Scientists hope that monitoring blood levels of BD-tau could facilitate screening and enrollment of patients from populations that historically haven't been included in research cohorts.

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Care Home Residents Surprised By Festive Penguins Bringing Christmas Cheer

Residents of a senior home got a flippin’ good surprise last week, after two charming feathered guests arrived to deliver some Christmas cheer. Seniors at the Colne View facility in Halstead, Essex, woke up to find two penguins outside. Accompanied by introductions using their adorable names, Pringle and Widget waddled through the halls, exploring the […]

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People sleep the least from early 30s to early 50s

People sleep less in mid-adulthood than they do in early and late adulthood, finds a new study.

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Can the AI driving ChatGPT help to detect early signs of Alzheimer's disease?

The artificial intelligence algorithms behind the chatbot program ChatGPT -- which has drawn attention for its ability to generate humanlike written responses to some of the most creative queries -- might one day be able to help doctors detect Alzheimer's Disease in its early stages. Research recently demonstrated that OpenAI's GPT-3 program can identify clues from spontaneous speech that are 80% accurate in predicting the early stages of dementia.

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Ottawa Nurse Wins $100,000 Cash From Radio Station–Watch Her Thrilling Reaction

A radio station in Canada surprised a nurse with the best holiday gift of her life. The young mother of two—with a third child on the way—heard the news through her phone while a colleague captured her reaction on video. The station in Ottawa known as Hot 89.9 chose Nicole as their Guaranteed Giveaway winner […]

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50 Years Ago, Apollo Crew Gave Humanity a Christmas Gift: Our First Gaze at ‘the Blue Marble’ Still Inspiring us Today

The astronauts of the Apollo 17 mission left a Christmas gift under the tree for all of humanity as they traveled on their way to the Moon. “The Blue Marble” is still one of the most inspiring images of our Earth ever taken, and it was 50 years ago on Christmas Eve that they did […]

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Smoking increases chances of mid-life memory loss, confusion

Middle-aged smokers are far more likely to report having memory loss and confusion than nonsmokers, and the likelihood of cognitive decline is lower for those who have quit, even recently, a new study has found.

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Characterizing rare, damaged cells that block functions of neighboring healthy cells

Senescent cells, which emerge after tissue injury, create an aged-like inflamed microenvironment that is negative for stem cell function and tissue repair. The finding provides a basis for mitigating the loss of muscle regenerative capacity in elderly people and for improving muscle repair in young healthy people.

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Man Spells Out ‘Hi Kevin’ in Lights for 20 Years–to Honor His Neighbor

Every Christmas, Mike Witmer gets out his colored lights to weave a very specific message out into the night. Witmer says passersby are sometimes confused by his lights, which read ‘Hi Kevin’ across his roof, but it’s to honor the memory of a young boy who passed away from cancer in 2010. For the past […]

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Head trauma, PTSD may increase genetic variant's impact on Alzheimer's risk

Researchers concluded that PTSD, TBI, and a specific variant of the APOE gene showed strong associations with Alzheimer's Disease and related dementias (ADRD).

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Digital detection of dementia: Using AI to identify undiagnosed dementia

Rising to meet the formidable challenge of the timely diagnosis of dementia, research scientists are conducting the Digital Detection of Dementia study, a real-world evaluation of the use of an artificial intelligence (AI) tool they developed for early identification of Alzheimer's disease and related dementias in primary care, the setting where most adults receive healthcare. Individuals identified as cognitively impaired will be referred for diagnostic services.

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Cognitively impaired degu is a natural animal model well suited for Alzheimer's research

A new study reveals that a long-lived Chilean rodent, called Octodon degus (degu), is a useful and practical model of natural sporadic Alzheimer's Disease.

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From Messi to Morocco: 5 Good News Stories From a Memorable World Cup

From Messi’s twilight triumph to bountiful showings of hospitality by the Qatari people, there was plenty to smile about during this year’s World Cup. As the curtain came down on the 2022 FIFA World Cup in Qatar, most fans of the sport will immediately look forward to enjoying the return of the domestic leagues, which […]

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Woman Who Hated Exercise Starts Lifting Weights to Help Combat Arthritis–And is Now a Regional Gold Medalist

A woman who hated exercise took up powerlifting to help combat her arthritis and is now slaying it as a commonwealth gold medalist in the sport. She says she’s now fitter than when she was in her 20s, and has now won gold, silver, and bronze medals in weightlifting. Arthritis prevented 58-year-old Kelly Clark from […]

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Patterns of lifespan weight gain/loss may predict dementia risk

Dementia is a growing global public health concern currently affecting 50 million people and is expected to rise dramatically to more than 150 million cases worldwide by 2050. Obesity, commonly measured by body mass index (BMI), continues to be a global epidemic and earlier studies suggested that obesity at midlife may lead to increased risk for dementia. But the association between BMI and the risk of dementia remains unclear. Now, researchers have found that different patterns of BMI changes over one's life course may be an indicator of a person's risk for dementia.

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Heartwarming Moment Ex-Foster Kid Asks to Be Adopted by Family He Sold a Car To

There’s no substituting the need for family, and one young man raised in the foster care system hoped to find one in a pair of perspective car buyers he met last year. Video shows the Wilkinsons family, who walked off the lot with a car and a new friend in April 2021, reacting tearfully to […]

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Looking for an early sign of LATE

Researchers provide new insights into the pathology of limbic predominate age-related TDP-43 encephalopathy, which mimics Alzheimer's, making it very difficult to identify in living patients.

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Captain Tom Moore’s Family Launches Online Bulletin Board Where Strangers Share Favorite Moments of Kindness

During the first COVID-19 lockdowns in England the late army captain, 99-year-old Sir Tom Moore, attempted to raise money for NHS Charities Together by walking across his garden 100 times. Now, believing that people need more positive and hopeful news in their life, his family is following in his footsteps by launching a Christmas campaign […]

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Strong connection to neighbors may improve health outcomes

Strong neighborhood connections reduced the negative impact of living alone on the death rates of older Chinese Americans, according to new researchers.

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Olfactory viral inflammation associated with accelerated onset of Alzheimer's disease

Viruses can inflame and disrupt connections between the olfactory system, which governs the sense of smell, and the part of the brain associated with memory and learning, possibly accelerating the onset of Alzheimer's disease, according to a new study.

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Employee Immediately Gives Her Favorite Shoes to Man Walking With Boxes on his Feet

The manager of a Minnesota liquor store was surprised to come back from lunch yesterday to find his counterhelp walking around in her socks. That’s because security camera footage revealed she had just given her favorite shoes—a pair of purple retro Jordans, to a homeless man she saw strapping boxes to his feet. Brooklyn Center […]

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Longevity treatments do not slow aging

Three approaches with a reputation for slowing aging processes have proven largely ineffective. For their study, researchers developed a new method to measure aging, which accounts for the complexity of aging in organisms.

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New immune culprit discovered in Alzheimer's disease

Cerebrospinal fluid, the brain's immune system, becomes dysregulated as we age and plays a newly discovered role in cognitive impairment in diseases such as Alzheimer's, a new study has found.

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Exercise, mindfulness don't appear to boost cognitive function in older adults

For decades, doctors and scientists have known that exercise is important for older adults -- it can lower risk for cardiac issues, strengthen bones, improve mood and provide other benefits. Likewise, mindfulness training reduces stress, and stress can be bad for the brain, so many have thought that exercise and/or mindfulness training might improve brain function. In a large study, researchers had hypothesized that if older adults exercised regularly, practiced mindfulness or did both, there might be cognitive benefits -- but that's not what they found.

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One-Armed Basketball Player Recruited for College Team Scores His First Points

On December 10th, teammates and fans of Northwestern State sounded their applause when their new freshmen basketball player scored his first points for the team. It was an extra special applause for the point guard, since Hansel Emmanuel has only one arm. A minute later he added to his total with a thunderous dunk in […]

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Who is more prone to recurrent UTIs? Bladder bacteria may be key

Researchers have identified specific bacteria in the bladder that may indicate which postmenopausal women are more susceptible to recurrent urinary tract infections (UTIs), and they found that estrogen may play a role in reducing that susceptibility.

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Frightening Relative of T-Rex is Discovered and Might be ‘Missing Link’ in Tyrannosaur Evolution

An evolutionary “missing link” species was just discovered, and it was a very big and scary link in a very big and famous chain. The newfound species, Daspletosaurus wilsoni, is thought to be the direct ancestor of Tyrannosaurus Rex, and had a unique set of facial features like a set of ridges called “hornlets” above its eye socket. […]

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Aging is driven by unbalanced genes

In a new study, researchers used artificial intelligence to analyze data from a wide variety of tissues, collected from humans, mice, rats and killifish. They discovered that the length of genes can explain most molecular-level changes that occur during aging.

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Residents of Tiny Village in Belgium Will be Sharing a Massive Lottery Win, Taking Home $915k Each–Tax Free

In the 1998 comedy Waking Ned Devine, a multi-million dollar lottery jackpot is split between the stunned residents of a tiny Irish village. Well, last week, the film’s storyline became a reality for the small Belgian village of Olmen, near Anterp. 165 Olmen residents divided up an unbelievable $150 million dollars won in the Euromillions […]

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New blood test can detect 'toxic' protein years before Alzheimer's symptoms emerge, study shows

Researchers can detect 'toxic' small aggregates of a particular protein in the blood of individuals with Alzheimer's disease, as well as in individuals who showed no signs of cognitive impairment at the time the blood sample was taken, but who developed it at a later date. This blood test picks up oligomers -- or small, misfolded aggregates -- of the amyloid beta protein, which scientists believe triggers the development of Alzheimer's.

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Estrogen may offer protection against delirium

Delirium is common among women with urinary tract infections (UTIs) -- especially those who have experienced menopause. Investigators, working with laboratory mice, have been able to prevent symptoms of the condition with estrogen, which is commonly used for hormone replacement therapy.

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Strangers Join Together to Rent 15-Passenger Van after Flight was Canceled–Take 10-hour Road Trip Instead

A determined mother’s positive thinking got her daughter home when her flight was canceled by helping to organize other stranded passengers to pitch in for a rental car. Alanah Story was set for a 7:00 PM flight from Orlando to Knoxville when like so many others this year, it was delayed, then canceled. Alanah’s mother […]

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'Sandwich generation' study shows challenges of caring for both kids and aging parents

Their older parents need care. Their kids are still under 18. And they probably have a job, too. They're the 'sandwich generation' -- a longtime nickname for the mostly female, mostly middle-aged group of Americans who serve as caregivers for both older and younger family members at once. A new study estimates there are at least 2.5 million of them, while giving a detailed view into who they are, and which older adults rely on them.

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After Debut Author’s Lonely Book Launch, Stephen King, Neil Gaiman and Margaret Atwood Swoop in With Support

New author Chelsea Banning tweeted to being “a little embarrassed” after the first book signing of her first book was attended by no one but her two friends. A blessing in disguise it was, as her tweet somehow attracted a large crowd of authors ranging from successful to legendary, sharing their own stories of book-signing […]

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Redesigning diabetes technology to detect low blood sugar in older adults with diabetes and Alzheimer's disease

A human factors engineer and health services researcher is developing and testing user-friendly health information tools and technology designed to enhance accessibility and value to older adults with both diabetes and Alzheimer's disease, and their caregivers. Without numerous finger sticks, these tools and technology will be designed to provide patients, caregivers, and clinicians with glucose metrics needed to diagnose hypoglycemia and identify treatment options.

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New study sheds light on how neurons respond to aged-related iron accumulation

A recent study details the neuronal response to excessive iron accumulation, which is associated with age-related neurodegenerative diseases.

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Twin ‘Saved Sister’s Life’ in Womb by Sending Distress Signal Forcing Early Delivery That Uncovered Major Problem

A twin saved her sister’s life while still in the womb, by sending out distress signals prompting doctors to deliver them early—which turned out to be critical for the other twin’s survival. Preemie Poppy McBride’s heart rate began to waver on the monitor at 31 weeks and five days into the pregnancy, which doctors say […]

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Pregnant moms' stress may accelerate cell aging of white, not Black, kids, study finds

Does stress during pregnancy impact children's cell aging, and does race matter? The answer is yes, according to a new study.

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World’s Oldest Pen Pals Turn 100, After 84 Years of Transatlantic Letters–And Now They’re Meeting on Zoom

The world’s oldest pen pals have both turned 100 years old, and are celebrating 80 years of letters sent across the pond. Geoff Banks from Devon, England, and American Celesta Byrne from New Jersey started writing to each other in 1938, when they were just 16-years-old. They were paired by an educational project that sought […]

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Childhood Best Friends Who Lost Touch Reunited 60 Years Later–in a Senior Care Home

Two childhood best friends who were ‘joined at the hip’ as kids were reunited over a half-century later—when they least expected it. Irene Gresty and Janet Henderson were neighbors in the 1940s, growing up in Linlithgow, West Lothian, England, but, like so many friendships, they lost touch over the years. Irene got married and moved […]

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Optimal blood tests for development of new therapies of Alzheimer's disease

A new study have identified which blood tests are best at detecting Alzheimer's disease during the earliest stages, and also other another blood test that are is optimal for detecting relevant treatment effects. These findings will speed up the development of new therapies that can slow down the disease progression.

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Young people make up greater proportion of COVID-19 deaths in 2021 compared to 2020

Since March 2020, COVID-19-related deaths claimed over a million lives in the U.S. alone. In the pandemic's early phases, most deaths were among older adults, but in 2021, deaths in younger persons increased while deaths in older persons decreased. A new study addresses this unexpected shift in COVID-19 mortality to relatively younger Americans and finds an increase in years of life lost due to COVID-19.

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To Help His Neighbors Save on Energy ‘Baker Ed’ Revives the Tradition of the Village Oven—Baking People’s Cakes for Free

A baker in the English town of Guisborough, pop. 17k or thereabouts, is reviving an ancient tradition to help his neighbors endure high energy costs. Thousands of years ago, societies built one oven in town where everyone went to bake their bread, and now Ed Hamilton-Trewhitt from Brickyard Bakery is offering to bake Christmas cakes […]

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How immune cells prevent cognitive decline

Mice altered to prevent the production of a particular type of immune cell struggled to form new memories.

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Early life experiences can have long-lasting impact on genes

Early life experiences can impact the activity of our genes much later on and even affect longevity, finds a new study in fruit flies.

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Socceroos Jumping For Joy After Historic Start to Australia’s Upstart World Cup Campaign

Australia have advanced to the knockout rounds of the World Cup for the first time since 2006, with coach Graham Arnold hailing his boys as a new “golden generation.” They now face a stiff test against one of the tournament favorites in Argentina this Saturday on just three-days rest. It would have been the safest […]

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Researchers identify the role of an Alzheimer's disease risk gene in the brain

A new study links a gene concentrated in the brain’s cleanup cells, known as microglia, to the inflammation that has increasingly emerged as a key mechanism contributing to Alzheimer’s disease. The findings may offer a new potential target for therapies for the intractable condition.

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Big data analysis powers the fight against Alzheimer's

New research findings help explain the progression of Alzheimer-related dementia in each patient. The findings outline a biological classification system that predicts disease severity.

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Bangladesh Farmers Digging Simple Wells Have Created an Irrigation Wonder of the World–With Rice Overflowing

Over the last 40 years, small-holder farmers in Bangladesh have, using very simple methods, turned the dry Bengal Basin into one of the richest croplands on Earth where two to three rice harvests can be had per year. They created a climate-resilient water system dubbed “The Bengal Water Machine” that has kept an underground reservoir […]

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The brain's immune cells can be triggered to slow down Alzheimer's disease

The brain's big-eating immune cells can slow down the progression of Alzheimer's disease.

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Machine learning gives nuanced view of Alzheimer's stages

Researchers used machine learning to pinpoint the most accurate means, and timelines, for anticipating the advancement of Alzheimer's disease in people who are either cognitively normal or experiencing mild cognitive impairment.

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Looking for a Meaningful Holiday Gift? Check Out the Kindness Book That Benefits Charity–Already $100K Raised

We’re always looking for books that inspire us to feel optimistic and positive about the world, and we are loving this one: HumanKind: Changing the World One Small Act At a Time. Author Brad Aronson was inspired to write HumanKind when his family went through one of the most difficult times of their lives. His […]

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25-Year-old Window Cleaner is Scrubbing Road Signs for Free to Improve Safety and Give Back to Community

A young man who started a window washing business has been cleaning road signs for free in his spare time to give back to his community. Liam Wildish started scrubbing signs in Maidstone, England this year, after launching his new window service—and he’s already become a notable local figure. “Some of the signs in Maidstone […]

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Guy Finds $40,000 Diamond Ring Buried on Florida Beach and Tracks Down the Owner Who Broke into Tears

A man was overjoyed when he discovered a diamond ring worth $40,000 on a beach in Florida last month, and soon became a metal detector angel. Joseph Cook found the ring buried in the sand at Hammock Beach in St Augustine and immediately posted a video he shot while digging it up to his social […]

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Family Swaps Their Mortgage for Motorhome to Travel USA and Have No Regrets While Saving $1,800 a Month

An American family that decided to sell their house and travel the country in a motorhome say they have no regrets, as well as a savings per year of more than $30,000. After renovating a 300 square foot motorhome in March 2021 they hit the road, homeschooling their kids, working remotely, and exploring the country. […]

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60-Year-Old Who Taught Herself to Play Guitar in Lockdown Launches Music Career with #1 Blues Single-LISTEN

A woman has found a new career in her 60s as a chart-topping musician just 2 years after teaching herself the guitar in lockdown. Kym Vincenti has since signed with a label and released three singles, one of which topped the blues charts on Apple Music. Vincenti had never picked up the instrument before April […]

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Great-Grandfather Dubbed ‘Super Mario’ Joined a Gym in Retirement and Still Pumps Iron at 94

A 94-year-old retiree still hits the gym twice a week to fit in a two-hour workout, and has no plans to stop. “Super” Mario Sanna considers the gym a “second home,” and the gym rats there his “second family.” The former railway engineer said his job laying train tracks kept him in good shape, but […]

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Long-term effects of COVID-19 in diabetics

Can a COVID-19 infection have long-term health effects on people with diabetes, including advancing their risk for heart disease? A recent article examines the mechanisms and possible effects of COVID-19 on patients with high-risk diabetes and the virus' potential to advance the disease, leading to inflammation and heart failure.

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Birth choices after previous cesarean and risk of pelvic floor surgery

Vaginal birth after a previous cesarean section is associated with an increased risk of pelvic floor surgery compared with planning another cesarean, according to a new study. The findings provide useful information to help women who have had a previous cesarean section when planning how to give birth in their next pregnancy.

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New study shows repeated stress accelerates aging of the eye

New research suggests aging is an important component of retinal ganglion cell death in glaucoma, and that novel pathways can be targeted when designing new treatments for glaucoma patients.

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Best Friends Win Million Dollar Lottery and Spread the Wealth in Hometown to Help Others

Besties JoAnn MacQueen and Marlisa Mercer won a million dollars playing the lottery, and immediately decided to keep the good vibes rolling by giving heaps and heaps of it away to the community. Identifying several causes and charities in their hometown of Orillia, in the Canadian province of Alberta to give fat checks to, local […]

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New study identifies connection between diabetes medications, multiple sclerosis

A study has found that anti-hyperglycemic medications used to treat Type 2 diabetes resulted in an increased risk of multiple sclerosis for people older than 45, particularly among women.

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Island Paradise of Tetiaroa Atoll Declared Rat-Free After Massive Volunteer Eradication Campaign

After more than three years of work, the Tetiaroa Atoll has been declared rat-free following a massive effort to poison off two invasive species devastating the ecosystem. The mission required the cutting of some 160 miles of trails across 1,250 acres of tropical atoll forest, and a team that were willing to suffer the bugs, […]

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Down syndrome, like Alzheimer's, is a double-prion disorder, study shows

The brains of people with Down syndrome develop the same neurodegenerative tangles and plaques associated with Alzheimer's disease and frequently demonstrate signs of the neurodegenerative disorder in their forties or fifties. A new study shows that these tangles and plaques are driven by the same amyloid beta and tau prions that researchers showed are behind Alzheimer's disease in 2019.

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New target for Alzheimer's therapies found

Researchers discover link between the protein medin and Alzheimer's disease.

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Study yields clues to why Alzheimer's disease damages certain parts of the brain

A study yields clues to why certain parts of the brain are particularly vulnerable to Alzheimer's damage. It comes down to the gene APOE, the greatest genetic risk factor for Alzheimer's disease. The parts of the brain where APOE is most active are the areas that sustain the most damage, they found.

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Gossypetin found in hibiscus may beat Alzheimer's disease

A research team has verified that gossypetin activates immune cells in the brain that clear A beta, which triggers Alzheimer's disease.

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Powerhouses of the cells: Mitochondria have a waste disposal mechanism to get rid of mutated mtDNA

A research team has identified a molecular target that could open up new therapeutic options to treat aging-associated diseases like Parkinson's.

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These States Allow Visitors Free Off-Road Wheelchairs In Their Parks and Nature Areas

Parks departments across the country are beginning to offer free all-terrain wheelchairs at their visitors centers for disabled people to explore their states’ treasures of nature. Such programs have already cropped up in Colorado, Michigan, and South Dakota, and Sleeping Bear Dunes National Lakeshore, a National Park Service unit, has also added off-road wheelchairs to […]

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Alzheimer's risk gene undermines insulation of brain's 'wiring'

In people carrying the APOE4 risk variant, a key brain cell type mismanages cholesterol needed to insulate neurons properly --another sign that APOE4 contributes to disease by disrupting lipids in the brain.

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Muscle strength tied to biological age, study shows

Muscle weakness marked by grip strength is associated with accelerated biological age, a new study suggests. Results were found using 'age acceleration clocks' based on DNA methylation, a process that provides a molecular biomarker and estimator of the pace of aging. Researchers say this suggests potential to adopt use of grip strength as a way to screen individuals for future risk of functional decline, chronic disease and early mortality.

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Ancient disease has potential to regenerate livers

Leprosy is one of the world's oldest and most persistent diseases but the bacteria that cause it may also have the surprising ability to grow and regenerate a vital organ. Scientists have discovered that parasites associated with leprosy can reprogram cells to increase the size of a liver in adult animals without causing damage, scarring or tumors. The findings suggest the possibility of adapting this natural process to renew aging livers and increase healthspan -- the length of time living disease-free -- in humans.

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Cat Walks Across France to Their Old Home Before Being Reunited With ‘Stunned’ Owners 13 Months Later

A cat traveled more than 280 miles to its old home before being reunited with her relocated owners and taken back to her new home—a whopping 13 months later. Laëtitia De Amicis moved with her family and their three cats because of work reasons a year ago, leaving the Orne region of France. The family […]

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A Baby Born Weighing 1.18-lb Has Finally Come Home After Spending 4 Months in Hospital Fighting for Life (LOOK)

A baby born weighing less than a loaf of bread at just 535 grams has finally returned home to sleep in her own room. Lauren Ormston’s pregnancy was initially smooth sailing. All her scans came back healthy—even the one at 20-weeks—and she expected to welcome her baby on July 1st. But on March 4, she […]

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Volunteers Etch Huge Poppies in Poignant Beach Tribute to War Heroes Ahead of Remembrance Day (11/11)

Volunteers carved a 100-foot mural of poppies onto a beach in a poignant tribute to the fallen ahead of Remembrance Day, November 11, which commemorates the formal end of the First World War on the 11th hour of the 11th day of the 11th month of 1918. Retired doctor and beach artist Claire Eason led […]

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Community Makes 10,000 Sandwiches for the Needy in 1 Day, Honoring Legacy of Woman Who Did That for Soldiers in WWI

A South Carolina community came together this week to make 10,000 sandwiches in one day to give away to local food banks, schools, soup kitchens, and shelters. The 200 volunteers in Greenville were also honoring the amazing legacy of Eugenia Duke, a local woman who bucked every norm 100 years ago to start a business […]

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Why older people are more susceptible to the flu

An inflammatory lipid appears to reduce the number of macrophages inside the lungs with age.

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Using SNAP benefits can help your memory, study finds

Eligible older adults who participate in the Supplemental Nutrition Assistance Program (SNAP) in the United States may have slower memory decline than eligible people who do not participate, according to a new study. Researchers found that those who used SNAP had about two fewer years of cognitive aging over a 10-year period compared with those who didn't use SNAP.

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Rejuvenated immune cells can improve clearance of toxic waste from brain

Rejuvenating the immune cells that live in tissues surrounding the brain improves fluid flow and waste clearance from the brain -- and may help treat or even prevent neurodegenerative diseases such as Alzheimer's and Parkinson's, according to a new study.

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Another Trucker is Named a Highway Angel for Rescuing Crash Victims After Witnessing High Speed Collision

A truck driver from Greenville, Texas, was named a ‘Highway Angel’ for stopping his travels to administer aid to two injured drivers after witnessing an incredible crash. One morning two weeks ago, Tony Doughty was driving eastbound on Interstate 40 near Albuquerque, when he witnessed a red car ram into a Jeep while going around […]

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New biomarker could help diagnose Alzheimer's disease early

A definitive diagnosis of Alzheimer's disease (AD) was once only possible after someone had died, but recent biomarker studies have led to the development of imaging and spinal fluid tests for those still living. However, the tests can only monitor severe disease, differentiating advanced AD from related disorders. Researchers have now identified a biomarker that could help physicians diagnose AD earlier, as a patient transitions into mild cognitive impairment (MCI).

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Hormone discovery could predict long term health of men

Researchers have discovered the vital role of a hormone, that develops in men during puberty, in providing an early prediction of whether they could develop certain diseases in later life.

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Nation’s Largest No-Kill Rescue Shelter Opens in Alabama to Save 5,000 Dogs a Year

These are Macon County Kennels, the largest no-kill rescue shelter in the U.S., and newly opened in Alabama to help combat a pet overpopulation crisis in the southeastern United States. It was renovated from an old greyhound training center into a facility that has the capacity to save, rehabilitate, and adopt out up to 5,000 […]

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Pyramid Made of 20 Tons of Plastic From Nile River Sparks Plan to Fund Massive Clean-ups

A different sort of great pyramid was just erected in Egypt’s Western Desert, which rather than enshrining a pharaoh’s glory, draws attention to the issue of plastic pollution. Constructed at the onset of what the builders hope will be a century of plastic cleanup, it also acts as a striking visual ahead of the annual […]

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Villagers Celebrate Reopening of Local Pub After 10 Years Raising 500K to Buy it–Halt its Tear-Down

Villagers are celebrating the reopening of their local pub after spending ten years raising 500K to buy it. Locals have spent a decade fighting to save The Rising Sun from being converted by property developers into new homes. The community group ‘Save Our Sun’ worked tirelessly with fundraisers and events to raise half the half […]

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A Homeless Man in Chicago Changed My Flat Tire: “He Really Saved Me”

One of the most popular posts this week on the massive Reddit community website evoked all the feels that come with a simple act of kindness—especially when the compassion is shown by a homeless man. The spontaneous helping hand was captured in a photo by a Reddit user who described the incident for folks on the […]

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Store Employee Angels are Rewarded for Assisting An Injured Elderly Woman: ‘I was Immediately Surrounded’

The Lowe’s hardware chain presented an Angel Award to employees in California who rallied around a customer that took a bad fall in the parking lot. Deborah Hayes told GNN that her elderly mother was shopping in the Modesto store when the accident occurred, and called the incident a “wonderful story of people helping others.” […]

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She Just Loves Cleaning and Now Helps Women in Need By Scrubbing Homes for Free While Traveling the World

A woman loves cleaning so much that she gave up her job and is now traveling the world scrubbing homes for free, helping women who need a huge hand. Auri Katariina was a service manager at a cleaning company in Finland in the summer of 2021, when she decided to quit and follow her unique […]

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Researchers offer roadmap for identifying new neuroprotective treatments by leveraging sex differences

Sex differences in the aging brain may offer an enticing clue for developing more effective neuroprotective treatments, according to a new research strategy.

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Chronic pain associated with poor health -- and COVID-19 infection -- decades later

People who suffer from chronic pain at age 44 are more like to report pain, poor general health, poor mental health outcomes and joblessness in their 50s and 60s, according to a new study.

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Teen Finds a Police Medal on Bottom of River–Tracks Down ‘Heartbroken’ Officer Who’d Been Robbed of it Last Year

A retired police officer who was heartbroken when thieves stole his Exemplary Service Medal last year was stunned when kind strangers tracked him down after they pulled it from a river in a “one-in-a-million” catch. 82-year-old Geoffrey Barron was devastated when burglars entered his home to steal valuables—and took the treasured medal that he’d been […]

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Honda Designers Make Fun Electric Car to Bring Joy to Hospitalized Kids as They Drive Themselves to Treatments–WATCH

At Children’s Health of Orange County, California, you need to be on the look-out for tots getting lab tests—because they’ll be tooting the horn at the wheel of their new electric Honda, which is bringing laughs and comfort to sick children. Designed by Honda engineers to ease the stress and anxiety of hospitalized children, the […]

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Scientists develop new mathematical model of Alzheimer's disease

Scientists have used a mathematical model to reveal how toxic proteins cluster together inside the brain during the early stages of Alzheimer's. The researchers say the discovery could have important implications for future treatments.

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Young Man Makes Wrong Turn, Then Saves Sleeping Family From Fire: ‘They’re safe because of him’

A driver who took a wrong turn was able to save the lives of four people after miraculously driving down their street and seeing their house on fire. A doorbell camera video captures the moment the young man from Omaha, Nebraska, ran around the house to start banging on windows, and calling 911. Brendan Birt […]

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I Waited 24 Years to Kiss My Childhood Best Friend–Now We’re Engaged After I Revealed My Secret

A woman who waited 24 years for a first kiss with her childhood best friend is now engaged to be married to him—after keeping her feelings a secret for over two decades. Kate MacNeil and Paul Damon were tied at the hip when they met as young teens in Williamsburg, Virginia in 1997. Despite the […]

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Sites in the brain where RNA is edited could help to better explain neurodevelopment and disease

Researchers have catalogued thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease.

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New technique helps ID genes related to aging

Researchers have developed a new method for determining which genes are relevant to the aging process. The work was done in an animal species widely used as a model for genetic and biological research, but the finding has broader applications for research into the genetics of aging.

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'A silent killer' -- COVID-19 shown to trigger inflammation in the brain

Researchers have found that COVID-19 activates the same inflammatory response in the brain as Parkinson's disease. The discovery identified a potential future risk for neurodegenerative conditions in people who've had COVID-19, but also a possible treatment.

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Scientists discover anti-inflammatory molecules that decline in the aging brain

Scientists reveal another factor implicated in the aging process -- a class of lipids called SGDGs (3-sulfogalactosyl diacylglycerols) that decline in the brain with age and may have anti-inflammatory effects. The research helps unravel the molecular basis of brain aging, reveals new mechanisms underlying age-related neurological diseases, and offers future opportunities for therapeutic intervention.

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Stunning Ancient Artwork Found at Site Sacked by ISIS –Assyrian War Plans Not Seen For 2,600 Years

In April, archeologists working in the ancient Assyrian city of Nineveh which had been destroyed by the Islamic State, uncovered a pulse-quickening discovery—a sealed gateway unknown in any previous excavations or surveys of the site. Carefully opening the door, the archeologists’ eyes fell on a hallway lined with dust that had not been disturbed for […]

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Spend the Night in a Giant Flower Pot – AirBnb is Funding The Most Off-Beat Lodgings

Would you ditch the Courtyard Marriot in order to sleep inside a giant flower pot? What about a nuclear missile bunker, a giant triceratops skull, or a pig sleeping under a quilt of grass and flowers? These are just some of the ideas that came out of the $10 million OMG! Fund from AirBnB, a […]

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Watch How Adult Elephants React to Birth in the Herd Just Moments After Adorable Baby is Born

For the first time in 8 years, the orphan-elephant heard in Kenya’s Sheldrick Wildlife Trust is welcoming a new infant, and the response was inspiring to witness. All elephants celebrate a new baby with great fanfare, but Sheldrick’s herd of former orphans took it to the next level. It has become a time-honored tradition for […]

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50-Year White House Groundskeeper is Surprised With Elm Tree Planted To Honor Him For 200 Years

Presidents come and go from these grounds outside the White House, but the beloved members of their staff—like Dale Haney—stay behind to serve the next First Family. The Bidens this week surprised this longtime groundskeeper who has cared for the White House Rose Garden, hundreds of trees, and more, for a half century. Befitting Haney’s […]

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Woman Discovers Exact Replica of Grandfather’s WWII Plane and Recreates 1942 Photo Before Getting a Special Ride

An Australian woman got the ride of a lifetime after discovering a replica of her grandfather’s World War II plane—and traveling 9,000 miles to recreate her favorite photo. Courtney Dohnt was never able to meet her Australian grandfather who fought alongside the Brits and Allied Forces, flying in a Hawker Hurricane. The plane—called Pegs after […]

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Cellular housekeeping process implicated in fatal neurological disorder

A study shows that as patients age, Huntington's disease impairs autophagy, which eliminates waste from cells. This housekeeping is significant in Huntington's because a buildup of waste in a specific kind of neuron leads to such cells' untimely deaths. The researchers also showed that enhancing the autophagy pathway in such neurons that were created from skin cells of Huntington's patients protects those cells from dying.

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New study expands range of potential Alzheimer's drugs

Alzheimer's disease is associated with a reduction of insulin receptors in brain microvessels, which may contribute to brain insulin resistance and the formation of amyloid plaques, one of the disease's hallmarks. The findings could affect the search for new Alzheimer's drugs.

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High Schooler Self-Publishes Fantasy Novel Over COVID Lockdowns to Distract Him From Video Games

Trying to distract himself from his PlayStation during COVID lockdowns, a London high schooler self-published a fantasy novel that’s now selling as far away as Australia. 16-year-old Dylan Brennan started writing Noble: Betrayed in April 2020, after recognizing he was spending too much time playing video games. The aspiring lawyer said he had long dreamt of […]

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Best evidence yet that lowering blood pressure can prevent dementia

A global study of over 28,000 people has provided the strongest evidence to date that lowering blood pressure in later life can cut the risk of dementia.

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One in 10 older Americans has dementia

In the first nationally representative study of cognitive impairment prevalence in more than 20 years, researchers found almost 10% of older adults have dementia and 22% have mild cognitive impairment.

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Billionaire MacKenzie Scott Donates $15m to Provide Glasses to Farmers With Blurry Vision in Developing Nations

Jeff Bezos’ former wife MacKenzie Scott has donated $15 million to provide hundreds of thousands of people with eyeglasses. It’s believed to be the largest private donation towards assisting uncorrected blurry vision, and will help mainly low-income tea, coffee, cocoa and artisan workers in India, Bangladesh, Ghana, Kenya and Uganda. While it might not be […]

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Young Girls Who Met on a Ship Sailing for America 75 Years Ago are Reunited: ‘I could never forget her’

It’s not uncommon for reunions to take place within a few years of the initial event—or maybe ten to twenty years after the first meeting. But a reunion after 75 years is truly astounding. That’s exactly what took place recently between immigrants Lena and Yolanda, who were young girls when they first met during a […]

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She Built a $15,000 Cottage in the Back Yard For a Brother With Autism: ‘The change has been incredible’

A woman built her brother a little house in her back garden and says it’s been a “game-changer” to give him the independence he needs. Tiffany Chou moved back to Hawaii from New York City to look after her 33-year-old brother, who has autism, after hearing that he was unhappy in his residential home. The […]

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Dwayne Johnson Surprises ‘Real-life Hero’ and Brings Him on TV to Honor His Services

An opportunity to meet Dwayne “The Rock” Johnson is a once-in-a-lifetime moment, but charity-superhero Yuri Williams got so much more than just a handshake when The Rock decided he wanted to do something special for him. Soon to hit the silver screen as a superhero himself, The Rock surprised Yuri on live TV, brought him […]

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Towering Statue Unveiled in London to Honor a National Hero You’ve Probably Never Heard of

Alongside Captain James Cook or Winston Churchill, a new statue in London’s iconic Southbank honors a British hero is not likely known, even by the British themselves. Unsung hero Jo Newby, 52, stands at Southbank in recognition of efforts in the child foster care system and youth special needs soccer. The statue was commissioned by […]

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Manipulating stress response in cells could help slow down aging

Scientists have found that a stress response in cells, when 'switched on' at a post-reproductive age, could be the key to slow down ageing and promote longevity.

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Novel PET imaging agent detects earliest signs of Alzheimer's disease

A new highly selective PET imaging agent can detect the presence of overexpressed monoamine oxidase-B (MAO-B) in cognitively unimpaired individuals with high beta amyloid -one of the earliest signs of Alzheimer's diseas-according to new research. The radiotracer, 18F-SMBT-1, allows for a better understanding of the role of inflammation in Alzheimer's disease, which can enable more accurate staging and prognosis at earlier stages.

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Weight change in early Parkinson's may be tied to changes in thinking skills

People who gain or lose weight soon after being diagnosed with Parkinson's disease may be more likely to have changes in their thinking skills than people who maintain their weight, according to a new study.

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Five hours' sleep a night linked to higher risk of multiple diseases

Getting less than five hours of sleep in mid-to-late life could be linked to an increased risk of developing at least two chronic diseases, finds a new study.

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Individualized fingerprints from sleep brainwaves provide a powerful new tool for understanding disease

A team led by researchers has developed a powerful computational tool for understanding brain health and disease, providing an enhanced way of characterizing the activity of the brain during sleep.

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275 Rare Parrots Saved From Hurricane at Florida Sanctuary: ‘They’re Family’

275 exotic parrots are now on their way to a new wildlife sanctuary after their heroic caretaker pulled all of them up into his stilted house like Noah’s Ark to ride out Hurricane Ian. There’s no question in Will Peratino’s mind that if he had not done so, the waves which crested his 5-foot high […]

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Brain discovery holds key to boosting body's ability to fight Alzheimer's, MS

Researchers have discovered a molecule in the brain responsible for orchestrating the immune system's responses to Alzheimer's disease and multiple sclerosis (MS), potentially allowing doctors to supercharge the body's ability to fight those and other devastating neurological diseases.

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Kindhearted Boy Used His Birthday Money to Start a Food Bank in His Garden Shed

A kind-hearted 11-year-old boy used his own birthday money to launch a foodbank service which he runs from his garden shed. Isaac Winfield fills bags of groceries which have been donated and hands them out to the needy around his hometown. Since starting the foodbank in 2020, the service has grown so much that Isaac’s […]

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He Taught Parents How to Play Drums and Bass So he’d Have People to Jam With–Now They Have Album–WATCH

A New Zealander taught both his parents how to play the drums and the bass so he would have people to jam with—and now they have an album out. Ryan Stokes couldn’t have his friends over to jam during lockdown so he decided to teach his parents how to play instruments. Inspired by The White […]

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Model demonstrates how RNA splicing defects contribute to Alzheimer's disease

Scientists have created a model to study the role of RNA splicing defects in Alzheimer's disease, revealing degeneration and toxicity caused by neuron hyperexcitability.

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Clusters of genes help mice live longer

Researchers have announced the discovery of multiple candidate genes that influence longevity. The discovery of genetic loci that influence longevity only in females is interesting and important, according to the researchers. Genetic loci are clusters of between 10 and 100 genes.

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Scientists detect dementia signs as early as nine years ahead of diagnosis

Scientists have shown that it is possible to spot signs of brain impairment in patients as early as nine years before they receive a diagnosis for one of a number of dementia-related diseases. The team analyzed data from the UK Biobank and found impairment in several areas, such as problem solving and number recall, across a range of conditions.

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Does the Mediterranean diet really decrease your risk of dementia?

A number of studies have suggested that eating a healthy diet may reduce a person's risk of dementia, but a new study has found that two diets including the Mediterranean diet are not linked to a reduced risk of dementia.

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Scientists shed light on COVID-19 booster dose effectiveness among the elderly in Japan

Vaccines against COVID-19 induce the immune system to produce neutralizing antibodies, and boosters ensure their continued production. Researchers from Japan now report that their elderly population produced a very low antibody titer when compared with the younger cohorts. They used a unique fingertip blood collection method to analyze whole blood for circulating antibodies against SARS-CoV-2. The researchers also propose a triage system to address the elderly patients with poor or low post-booster immune response.

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How a Tiny Injured Cat Kickstarted an Entire Sustainability Initiative

It’s so easy to pantomime corporations as mass polluters of the environment, but they’re run by humans, who reacted exactly as anyone else would when they saw a picture of Munchkin the orange Tabby. The stray kitten was taken in by rescuers after it was found with a plastic packaging ring from a Munchkin “Any […]

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Study explores links between people taking multiple medications and dementia diagnosis

A study has provided an in-depth exploration of the links between evolving polypharmacy -- which involves a patient being prescribed more than one drug at any given time -- and a dementia diagnosis.

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Healthy aging requires an understanding of personality types

New research shows that older adults may be better supported as they age when their personalities are considered -- for example, are they more like orchids or dandelions? Researchers examined the potential effects of lifestyle activities on the cognitive health of more than 3,500 adults aged 60+, and found that personality -- using psychology's orchid-dandelion metaphor -- can be a factor in how well supportive programs work.

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Blood levels of 'free range' DNA may signal early detection of dementia and frailty

In a long-term prospective study of more than 600 older participants, researchers say they have evidence that higher levels of cell-free DNA circulating in the blood may signal increased risk of chronic inflammation associated with early signs of frailty and dementia.

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She Finally Met Her Long Lost Dad, Who Didn’t Know She Existed, Thanks to Stranger on Facebook

A woman finally met her long-lost dad, a man who didn’t even know she existed—thanks to an amateur sleuth she met on Facebook. Adrieanna Tyler thought she knew her father until the age of 13, when she overheard him referring to her as his stepdaughter. Since then, she wanted to know who her biological father […]

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Youth Given 8 Months to Live Has Beaten Aggressive Blood Cancer, Now Inspires Others: ‘You can get through anything’

A young Florida man given just eight months to live has beaten a rare and aggressive blood cancer, after nearly dying multiple times during treatments. Now he is inspiring others who are going through health hardships. Michael Cramer went to see a doctor after suffering fatigue, night sweats, and weight loss—symptoms he thought were caused […]

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Novel treatment effective for bladder cancer, study in mice shows

An epigenetics drug currently being used for the treatment of blood cancers and rare sarcomas can stop the growth of bladder cancer by activating the immune system, reports a new study in mice. The drug is now being tested in a national clinical trial for patients with late-stage bladder cancer.

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Age vs. genetics: Which is more important for determining how we age?

Our genetics, the environment and our age all play important roles in our health, but which of these is the most important? A new study suggests that in many cases, age plays a more important role than genetics in determining which genes in our bodies are turned on or off, influencing our susceptibility to disease.

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Detecting Alzheimer's disease from blood samples

Researchers have developed a method to detect build-up of amyloid beta in the brain, a characteristic of Alzheimer's disease, from biomarkers in blood samples.

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Ukraine Girl Bereft Without Her Cat is Reunited Thanks to Kind Strangers in 5 Countries and 7,000 Miles–WATCH

A truly astonishing story of war-time goodwill to mend a 10-year-old’s broken heart will bring a tear to almost anyone’s eyes. Nearly a dozen people, most of whom never met little Agnessa, all took turns helping to get her cat Arsenii travel-ready, out of Ukraine, across Europe, across the Atlantic Ocean, and all the way […]

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Schizophrenia may increase dementia risk by 2.5 times

People with psychotic disorders such as schizophrenia are 2.5 times more likely than those without a psychotic disorder to eventually develop dementia, according to a new review.

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Study links omega-3s to improved brain structure, cognition at midlife

Healthy study volunteers whose red blood cells contained higher concentrations of omega-3 fatty acids were found to have better brain structure and cognitive function in middle age.

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Scientists discover dual-function messenger RNA

A new study has discovered an unprecedented pathway producing telomerase RNA from a protein-coding messenger RNA (mRNA).

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New study underscores need for COVID-19 booster shots for older adults

In a study of more than 80 men and women from Baltimore, Maryland, researchers have added to evidence that COVID-19 booster shots are essential for maintaining long-term immunity against infection, particularly among older adults.

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Decreased proteins, not amyloid plaques, tied to Alzheimer's disease

New research supports the hypothesis that Alzheimer's disease is caused by a decline in levels of a protein called amyloid-beta.

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Mouse study explores Alzheimer's link to the X chromosome

Evidence in mice and human brain tissue reveals a mechanism that may explain the sex-based differences in Alzheimer's disease, including why females are more vulnerable. Researchers report that female brains show higher expression of an X-linked enzyme called ubiquitin-specific peptidase 11 (USP11) compared to males, resulting in greater accumulation of a protein called tau.

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Retiring increases amount of sleep and decreases physical activity

Researchers used accelerometers to study how the 24-hour movement behaviors, i.e. sleep, sedentary behavior, light physical activity and moderate-to-vigorous physical activity change in relation to each other when a person retires. The results show an increase in the amount of sleep, which contributed to decreased amount of physical activity.

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Lonely 67-Year-Old Sets Up Woodworking ‘Shed’ to Combat Loneliness in Men, Following World Trend

Across the English speaking world, men are learning that the easiest way to cure a bout of social isolation is not by talking face to face, but shoulder to shoulder. When Phillip Jackson moved back to England from Australia, he was 67, and immediately felt like a stray dog in his native town of Barnsley. […]

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Role of genomic changes in specific brain cells in Alzheimer's disease

A large study has looked at DNA methylation in Alzheimer's disease. DNA methylation is the process by which the activity of genes is regulated, acting a bit like a dimmer-switch to turn genes on or off. Increasingly, this process is thought to have a key role in the development of diseases such as dementia.

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Biomarkers used to track benefits of anti-aging therapies can be misleading, suggests nematode study

Researchers followed the birth and death of tens of thousands of nematode worms using the 'Lifespan Machine', which collects lifespan data at unprecedented statistical resolution. They found that worms have at least two distinct 'biological ages', and that these have consistent correlations between each other, suggesting the existence of an invisible hierarchical structure that regulates the ageing process. The findings challenge the idea of living organisms having a single, universal biological age. It also means mean that biomarkers used to assess biological age can be changed by interventions such as diet, exercise, or drug treatments without actually turning a 'fast ager' into a 'slow ager'. The study calls into question the use of ageing biomarkers -- what exactly are they measuring?

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Young women who reduce binge drinking could decrease risk of COVID-19 infection, study shows

New research correlates substance-use patterns and personal characteristics with COVID-19 impacts.

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SuperAger brains contain 'super neurons'

Neurons in an area of the brain responsible for memory were significantly larger in SuperAgers compared to cognitively average peers, individuals with early-stage Alzheimer's disease and even individuals 20 to 30 years younger than SuperAgers -- who are aged 80 years and older, reports a new study. The study of was the first to show that these individuals carry a unique biological signature that comprises larger and healthier neurons in the entorhinal cortex that are relatively void of tau tangles.

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He Finally Located Source of Mysterious Sound–A New Frog Species Named After His Rewilding Quest in Costa Rica

A nature-lover’s well-trained ears led to the discovery of a new species of frog, after the Costa Rican man searched for six months to find the source of a mysterious sound. The tiny green frog was discovered by Donald Valera Soto, a naturalist and co-owner of Tapir Valley Nature Reserve, a cattle ranch that he […]

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With fractured genomes, Alzheimer's neurons call for help

Ailing neurons plagued with an accumulation of double-strand breaks in their DNA may instigate an inflammatory response from the brain's microglia immune cells, a new study shows.

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One in three Alzheimer's disease family caregivers has persistent symptoms of depression

More than 60% of family caregivers of individuals with Alzheimer's disease (AD) experienced at least mild depressive symptoms already at the time the individual with AD was diagnosed. In one third of them, depressive symptoms worsened during a five-year follow-up.

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Breaks in 'junk' DNA give scientists new insight into neurological disorders

'Junk' DNA could unlock new treatments for neurological disorders as scientists discover its breaks and repairs affect our protection against neurological disease.

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John Cena Smashes Guinness World Record – Granting 650 Wishes for Sick Children

American actor and WWE superstar John Cena has set a new record for the most wishes granted through the Make-A-Wish Foundation with 650. The Make-A-Wish Foundation helps fulfill the wishes of children who have been diagnosed with a critical illness. As the most wished-for celebrity, nobody else has ever granted more than 200 wishes in the 42-year […]

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Youth Crime in the U.S. Has Plummeted 78% Since 1994, Which Counters the Usual Narrative

A recent report found that the number of youth arrests for violent crime continued to decline in 2020 and was down 78% from its peak in 1994. Analysis of the data from the FBI found that people aged 17 and younger accounted for just 7% of all arrests for violent crime like murder and robbery […]

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Fasting-mimicking diet reduces signs of dementia in mice

Cycles of a diet that mimics fasting appear to reduce signs of Alzheimer's in mice genetically engineered to develop the illness, according to a new study. Short cycles of a low-calorie diet that replicates fasting appeared to reduce inflammation and delay cognitive decline in mouse models of Alzheimer's disease; initial data indicates diet's safety in Alzheimer's patients.

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Disarming the immune system's lethal lung response

Neutrophils are the body's first line of defense against infection. But if too many attack for too long, they can damage the tissues they're meant to protect. In the lungs, this damage can lead to acute respiratory distress syndrome, the leading cause of death due to COVID-19. Researchers have found that using a drug to inhibit a protein called PTP1B can prevent lethal lung inflammation in mice. This discovery may lead to better treatments for severe inflammatory conditions like sepsis and COVID-19.

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COVID-19 associated with increase in new diagnoses of type 1 diabetes in youth, by as much as 72 percent, study finds

Children who were infected with COVID-19 show a substantially higher risk of developing type 1 diabetes (T1D), according to a new study that analyzed electronic health records of more than 1 million patients ages 18 and younger.

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How does what we eat affect our healthspan and longevity? It's a complex dynamic system

The answer to a relatively concise question -- how does what we eat affect how we age -- is unavoidably complex, according to a new study. While most analyses had been concerned with the effects of a single nutrient on a single outcome, a conventional, unidimensional approach to understanding the effects of diet on health and aging no longer provides us with the full picture: healthy diet needs to be considered based on the balance of ensembles of nutrients, rather than by optimizing a series of nutrients one at a time. Until now little was known about how normal variation in dietary patterns in humans affects the aging process.

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More older adults should be checking blood pressure at home, study suggests

Only 48 percent of people age 50 to 80 who take blood pressure medications or have a health condition that's affected by hypertension regularly check their blood pressure at home or other places, a new study finds. A somewhat higher number -- but still only 62 percent -- say a health care provider encouraged them to perform such checks.

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Researchers advance efforts to tailor drug delivery to cells' 'power plants'

In a study using lab-grown cells, researchers specializing in aging report they have successfully delivered a common blood pressure drug directly to the inner membrane of mitochondria, the 'power plants' in the cells of humans, animals, plants and most other organisms.

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Former Debt Collectors Have Wiped Away $6.7 Billion of Medical Debt for Millions of Americans

A dynamic duo from Wall Street has just passed a huge milestone in charitable history, completely paying off the medical debt for some 3.6 million Americans—a do-good revolution from two guys who used to be debt collectors themselves. It was the Occupy Wall Street movement that first stirred the hearts of Jerry Ashton and Craig […]

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Former Debt Collectors Have Wiped Away $6.7 Billion of Medical Debt for Millions of Low-Income Americans

The country’s largest charity for paying off medical debt has just passed a huge milestone that leaves the jaw agape—3.6 million Americans whose medical debt has been zeroed by, of all people, two former Wall Street debt collectors. It was 2011’s Occupy Wall Street movement that first stirred the hearts of Jerry Ashton and Craig […]

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COVID-19 infections increase risk of long-term brain problems

A comprehensive analysis of federal data shows people who have had COVID-19 are at an elevated risk of developing neurological conditions within the first year after infection. Movement disorders, memory problems, strokes and seizures are among the complications.

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Artificial intelligence used to uncover the cellular origins of Alzheimer's disease and other cognitive disorders

Deep learning models represent 'an entirely new paradigm for studying dementia.'

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Newly identified small molecules break amyloid tangles that cause Alzheimer's

In lab experiments, researchers observed a molecule called EGCG break up tau tangles extracted from Alzheimer's disease brain tissue EGCG does not, however, easily penetrate the human brain. They found two other molecules -- CNS-11 and CNS-17 -- that work like EGCG to stop tangles spreading cell to cell but are better leads for drugs.

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Nightmares in middle age linked to dementia risk

People who experience frequent bad dreams in middle age are more likely to be diagnosed with dementia later in life, according to research at the University of Birmingham.

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Southwest Airlines Workers Looked After a Passenger’s Pet Fish for 4 Months After it was Banned From Flight

A pair of Southwest Airline employees volunteered to become mom and dad to a passenger’s fish after the passenger was told she could not embark with the animal. Kira was returning home from her Freshman year at college with her beta fish Theo when she was told it was not allowed on her flight. That’s […]

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Genetic variants linked to congenital urinary tract obstruction in males

Genetic variation affecting developmental genes not previously linked to urethral development may contribute to a congenital condition that is the most common cause of kidney failure in young males, a new study suggests.

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He Invented a $2 Paper Microscope For Remote Lab Work So Scientists Don’t Have to Haul Heavy Equipment

A young scientist who worked in the jungles of Thailand has been awarded a national prize for his invention of a $2 paper microscope that can be taken on field expeditions. If a scientist wants to study something at the microscopic level, they need a microscope, which if they are deep in the Amazon Rainforest […]

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New study explains link between diabetes and UTIs

Lower immunity and recurring infections are common in type 1 and type 2 diabetes. Researchers now show that the immune system of people with diabetes has lower levels of the antimicrobial peptide psoriasin, which compromises the urinary bladder's cell barrier, increasing the risk of urinary tract infection.

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Nebraska Man Makes World’s Longest Journey by Pumpkin Boat on 60th Birthday

On the morning of August the 27th, a Nebraska man woke up on his 60th birthday with a single goal—to raft the mighty Missouri in a giant pumpkin. This is not the start to a collaborative work between Roald Dahl and Mark Twain, but rather the Guinness World Record-breaking stunt by giant pumpkin enthusiast Duane […]

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Toddler Given Cancer Prognosis of 6-12 Months Defies the Odds to be Declared Cancer-Free in 8 Months

A toddler given a prognosis of six to 12 months to live after doctors found a tumor has defied the odds and been declared cancer-free. In April of 2021, Leanne Waite and her husband, Chris, were dressing their three-year-old son when they noticed his left arm was in severe pain after it got caught in […]

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New Poll Reveals The Secret to Happiness is Practicing Gratitude

The secret to maximum happiness may be expressing gratitude, a new poll suggests. The random double-opt-in survey of 2,000 Americans looked at the potential connection between gratitude and happiness — revealing that 65% of respondents who report that they’re “very happy” on a daily basis were more likely to “always” give thanks. While looking at […]

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The Guam Kingfisher Could Soon Return to the Wild After a 30-Year Absence Thanks to Ambitious Scientists

A long shot rescue plan for the Critically-Endangered Guam kingfisher is set to take place on the wilds of an island nowhere near Guam. Having been extirpated from Guam via invasive brown tree snakes, captive breeding centers have kept the species treading water until now. A scientific mission born of a partnership between the Nature […]

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Repeated infections associated with increased risk of some neurodegenerative diseases

Infections treated with specialty hospital care in early- and mid-life are associated with an increased subsequent risk of Alzheimer's (AD) and Parkinson's diseases (PD), but not amyotrophic lateral sclerosis (ALS), according to a new study.

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Daily multivitamin may improve cognition and possibly protect against decline, study suggests

New research shows that taking a daily supplement may improve cognition in older adults. In the study, researchers estimated that three years of multivitamin supplementation roughly translated to a 60-percent slowing of cognitive decline (about 1.8 years).

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Researchers identify immune cell that helps kill bladder cancer tumors

Researchers have made two important discoveries about the mechanism by which bladder cancer cells foil attacks from the immune system. The research could lead to a new therapeutic option for patients with these types of tumors.

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Author Spends Lifetime Searching for Woman Who Taught Him to Read, and Then She Surprised Him

Author Jamil Jan Kochai tried for years to reconnect with his second grade teacher—a woman whom he credits with all the success he has had in life. Why is this? Mrs. Lung stayed after hours in their Sacramento elementary school to teach Kochai one-on-one how to read and write, something she managed in a just […]

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Risk factor for developing Alzheimer's disease increases by 50-80% in older adults who caught COVID-19

Older people who were infected with COVID-19 show a substantially higher risk -- as much as 50% to 80% higher than a control group -- of developing Alzheimer's disease within a year, according to a study of more than 6 million patients 65 and older.

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New research estimates the overall disease burden of genetic risk factors

Researchers have, for the first time, systematically estimated the impact of a range of different disease-associated genetic risk factors on the loss of healthy life years. Knowing the contribution of different genetic risk factors on disease burden can help prioritise and design interventions using genetic information.

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Significant risk of sensory loss in long COVID, study finds

New research has revealed the extent of sensory loss among people suffering from long COVID, with around 30 percent reporting a decreased sense of smell, and a similar number finding their sense of taste continuing to be affected 12 weeks or more after the initial infection.

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Man Tracks Down Teen Who Mugged His Nephew to See if He Would Turn His Life Around

A man tracked down the teen knifeman who mugged his nephew and rather than hand him in, spoke to him about turning his life around. After listening to the remorseful youth’s story, Winston Davis has been inundated with job offers for the lad to keep him away from crime. It took Davis six weeks to […]

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Scientists discover how cells repair longevity-promoting 'recycling system'

Researchers described a pathway by which cells repair damaged lysosomes, structures that contribute to longevity by recycling cellular trash. The findings are an important step towards understanding and treating age-related diseases driven by leaky lysosomes.

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High blood pressure may accelerate bone aging

A new study in mice found that hypertension may be linked to significant bone loss. Bone quality in young mice with high blood pressure was similar to the bones of older mice without high blood pressure, suggesting that the effects of hypertension on bone quality, which includes strength, may mimic that of aging. The researchers suggest early detection and treatment of high blood pressure may help to deter loss of bone quality as people age.

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How a single protein could unlock age-related vision loss

Researchers are helping to reveal the molecular secrets of macular degeneration, which causes almost 90% of all age-related vision loss.

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Grandma Lost 250 Pounds and is Now a Bodybuilder After Saggy Skin Removal

Unable to get around without a walker, an English Granny has gone on to shed 250 pounds, have 28 pounds of saggy skin removed, and is now a professional bodybuilder. Years ago, Dee Hodgson’s size used to leave her in constant agony, and doctors suspected she was suffering from fibromyalgia, a long-term condition that causes […]

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