Thursday, March 17, 2022

Alzheimer’s: Protective immune cells active decades before symptom onset

In individuals with a genetic predisposition to Alzheimer's disease, the immune cells of the brain -- the 'microglia' -- start exerting a protective effect up to two decades before the first symptoms appear. A team draws this conclusion based on a study of more than 200 volunteers. In light of their study data, the scientists consider modulating the activity of microglia to be a promising therapeutic approach. To this end, they aim to develop drugs that target a cellular receptor called TREM2.

from Healthy Aging News -- ScienceDaily https://ift.tt/YsF3mbk

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