Tuesday, January 16, 2024

Unraveling the role of supersulfides in regulating mitochondrial function and longevity

Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.

from Healthy Aging News -- ScienceDaily https://ift.tt/wTuKmra

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