With fractured genomes, Alzheimer's neurons call for help

Ailing neurons plagued with an accumulation of double-strand breaks in their DNA may instigate an inflammatory response from the brain's microglia immune cells, a new study shows.

from Healthy Aging News -- ScienceDaily https://ift.tt/j08XDhn

One in three Alzheimer's disease family caregivers has persistent symptoms of depression

More than 60% of family caregivers of individuals with Alzheimer's disease (AD) experienced at least mild depressive symptoms already at the time the individual with AD was diagnosed. In one third of them, depressive symptoms worsened during a five-year follow-up.

from Healthy Aging News -- ScienceDaily https://ift.tt/A9smRzU

Breaks in 'junk' DNA give scientists new insight into neurological disorders

'Junk' DNA could unlock new treatments for neurological disorders as scientists discover its breaks and repairs affect our protection against neurological disease.

from Healthy Aging News -- ScienceDaily https://ift.tt/VmTs9tN

John Cena Smashes Guinness World Record – Granting 650 Wishes for Sick Children

American actor and WWE superstar John Cena has set a new record for the most wishes granted through the Make-A-Wish Foundation with 650. The Make-A-Wish Foundation helps fulfill the wishes of children who have been diagnosed with a critical illness. As the most wished-for celebrity, nobody else has ever granted more than 200 wishes in the 42-year […]

The post John Cena Smashes Guinness World Record – Granting 650 Wishes for Sick Children appeared first on Good News Network.

from Good News Network https://ift.tt/xNZektd

Youth Crime in the U.S. Has Plummeted 78% Since 1994, Which Counters the Usual Narrative

A recent report found that the number of youth arrests for violent crime continued to decline in 2020 and was down 78% from its peak in 1994. Analysis of the data from the FBI found that people aged 17 and younger accounted for just 7% of all arrests for violent crime like murder and robbery […]

The post Youth Crime in the U.S. Has Plummeted 78% Since 1994, Which Counters the Usual Narrative appeared first on Good News Network.

from Good News Network https://ift.tt/4afwP67

Fasting-mimicking diet reduces signs of dementia in mice

Cycles of a diet that mimics fasting appear to reduce signs of Alzheimer's in mice genetically engineered to develop the illness, according to a new study. Short cycles of a low-calorie diet that replicates fasting appeared to reduce inflammation and delay cognitive decline in mouse models of Alzheimer's disease; initial data indicates diet's safety in Alzheimer's patients.

from Healthy Aging News -- ScienceDaily https://ift.tt/DzsZTbG

Disarming the immune system's lethal lung response

Neutrophils are the body's first line of defense against infection. But if too many attack for too long, they can damage the tissues they're meant to protect. In the lungs, this damage can lead to acute respiratory distress syndrome, the leading cause of death due to COVID-19. Researchers have found that using a drug to inhibit a protein called PTP1B can prevent lethal lung inflammation in mice. This discovery may lead to better treatments for severe inflammatory conditions like sepsis and COVID-19.

from Healthy Aging News -- ScienceDaily https://ift.tt/6kioDdw