'Is amyloid precursor protein the mastermind behind Alzheimer's or is it just an accomplice?' Researchers devised a multi-functional reporter for amyloid precursor protein and tracked its localization and mobility, noticing a strange association between the protein and cholesterol that resides in the cell membrane of synapses. With cholesterol's broad involvement in almost all aspects of neurons' life, they propose a new theory on the amyloid precursor protein connection in AD, especially in the surface of those tiny synapses, which triggers neurodegeneration.
from Healthy Aging News -- ScienceDaily http://bit.ly/2XClaq4
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